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CAL-101 (Idelalisib, GS-1101)

InhA, Func 870281-82-6
产品编号 ABIN3220302
发货至: 中国
  • 应用范围
    Inhibition Assay (InhA), Functional Studies (Func)
    原理
    CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM, shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
    产品特性
    Target: PI3K inhibitor, mTOR inhibitor
    Receptor: PI3Kα/β/δ/γ, mTOR
    纯化方法
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    纯度
    98 %
    Formula
    C22H18FN7O
    Solubility
    DMSO ≥80mg/mL
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    储存条件
    -20 °C
    储存方法
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    有效期
    24 months
  • 背景
    PI3K/Akt/mTOR Signaling
    分子量
    415.42 g/mol
    CAS-编号
    870281-82-6
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