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AT9283

InhA, Func 896466-04-9
产品编号 ABIN3220130
发货至: 中国
  • 应用范围
    Inhibition Assay (InhA), Functional Studies (Func)
    原理
    AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays, also potent to Aurora A/B, Abl(T315I). Phase 2.
    产品特性
    Target: JAK inhibitor, Aurora Kinase inhibitor, Bcr-Abl inhibitor, GSK-3 inhibitor, FGFR inhibitor
    Receptor: JAK3,JAK2,Aurora A,Aurora B,Abl1,GSK-3β, FGFR2,VEGFR3/FLT4
    纯化方法
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    纯度
    98.45 %
    Formula
    C19H23N7O2
    Solubility
    DMSO 76 mg/mL,Ethanol 38 mg/mL,Water <1 mg/mL
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    储存条件
    -20 °C
    储存方法
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    有效期
    24 months
  • 背景
    Angiogenesis,JAK/STAT Signaling
    分子量
    381.43 g/mol
    CAS-编号
    896466-04-9
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