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CASP5 蛋白

(Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010].
CASP5 Protein (AA 309-418) (GST tag) CASP5 Protein (AA 309-418) (GST tag) CASP5 Protein (AA 309-418) (GST tag) (ABIN1348109)

CASP5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

CASP5 Protein (AA 347-434) (His tag) CASP5 Protein (AA 347-434) (His tag) CASP5 Protein (AA 347-434) (His tag) (ABIN3090740)

Crystallography grade CASP5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

CASP5 Protein (AA 137-327) (His tag) CASP5 Protein (AA 137-327) (His tag) CASP5 Protein (AA 137-327) (His tag) (ABIN3090739)

Crystallography grade CASP5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

CASP5 蛋白 by Grade

Find CASP5 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CASP5 蛋白 by Origin

Find CASP5 蛋白 for a variety of species such as anti-Human CASP5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASP5 蛋白 by Source

Here you will find CASP5 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CASP5 蛋白 by 蛋白类型

Here you can find CASP5 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CASP5 蛋白 by 应用范围

Find CASP5 蛋白 validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CASP5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348109
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090740
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090739
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391987
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713310
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709203
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CASP5 蛋白

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Aliases for CASP5 蛋白

caspase 5 (CASP5) 蛋白
caspase-5 (LOC100437308) 蛋白
CASP5 蛋白
ICE(rel)III 蛋白
ICEREL-III 蛋白
ICH-3 蛋白
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