HsTx1
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- 抗原
- HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))
- 应用范围
- Blocking Reagent (BR)
- 原理
- HsTx1 is a Kv1.3 channel blocker
- 序列
- Ala-Ser-Cys3-Arg-Thr-Pro-Lys-Asp-Cys9-Ala-Asp-Pro-Cys13-Arg-Lys-Glu-Thr-Gly-Cys19-Pro-Tyr-Gly-Lys-Cys24-Met-Asn-Arg-Lys-Cys29-Lys-Cys31-Asn-Arg-Cys34-NH2Disulfide bonds between Cys3-Cys24, Cys9-Cys29,Cys13-Cys31 and Cys19-Cys34
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- 限制
- 仅限研究用
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- 抗原
- HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))
- 别名
- HsTx1
- 背景
- HsTx1 is a member of the a-KTx6 family of toxins active on voltage-gated K+ v1.3 channels (Kd close to 10 pM). It is also very active on Kv1.2 channels (Kd around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on K channels.
- 分子量
- 3819.87 Da
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