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抗Human Interleukin 6 抗体:
抗Mouse (Murine) Interleukin 6 抗体:
抗Rat (Rattus) Interleukin 6 抗体:
Human Monoclonal Interleukin 6 Primary Antibody for FACS - ABIN1383944
Lu, Brochier, Wijdenes, Brailly, Bataille, Klein: High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo. in European journal of immunology 1992
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042620
Xu, Feng, Wang, Zhu, Lin, Lou, Xiang, He, Zheng, Tang, Zuo: Phytoestrogen calycosin-7-O-?-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. in Journal of cellular biochemistry 2011
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Rat (Rattus) Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042526
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
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Human Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3043090
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for ELISA, WB - ABIN3043248
Shi, Song, Zhang, Li, Li: Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients. in Experimental and therapeutic medicine 2013
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Human Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042806
Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. in International journal of clinical and experimental pathology 2015
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Human Polyclonal Interleukin 6 Primary Antibody for ICC, IF - ABIN269335
Bottino, Balamurugan, Tse, Thirunavukkarasu, Ge, Profozich, Milton, Ziegenfuss, Trucco, Piganelli: Response of human islets to isolation stress and the effect of antioxidant treatment. in Diabetes 2004
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Human Monoclonal Interleukin 6 Primary Antibody for CyTOF, FACS - ABIN4900155
Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. in The Journal of allergy and clinical immunology 2009
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Human Monoclonal Interleukin 6 Primary Antibody for CyTOF, FACS - ABIN4900156
Rodier, Coppé, Patil, Hoeijmakers, Muñoz, Raza, Freund, Campeau, Davalos, Campisi: Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. in Nature cell biology 2009
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for IF (p), IHC (p) - ABIN728083
Sun, Zeng, Cao, Song, Zhang, Liu: Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue. in BioMed research international 2015
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Results show that IL-6 regulates PTTG1 (显示 PTTG1 抗体) expression via activated STAT3 (显示 STAT3 抗体) directly binding to the region -500 to +1 of PTTG1 (显示 PTTG1 抗体) promoter in androgen-dependent prostate cancer cells.
High IL-6 expression is associated with invasiveness of pancreatic intraepithelial neoplasia and cancer.
Over-expression of IL-6 is correlated with hepatic dysfunction, variceal bleeding and p-STAT3 (显示 STAT3 抗体) expression in cirrhotic patients.
This meta-analysis shows that IL-6-174G > C SNP is significantly associated with increased RA risk in overall, and specifically in Asian population.
IL-6 levels may be associated with internalizing disorders in youths and suggests that inflammation might be an early biomarker of emotional distress; differences between groups in IL-10 (显示 IL10 抗体) levels were not statistically significant
Inter-group comparisons of cytokine levels demonstrated no significant differences in TNF-alpha (显示 TNF 抗体), IL-6 and IL-8 (显示 IL8 抗体) cytokines levels. IL-10 (显示 IL10 抗体) level showed a moderately significant increase in the modified St. Thomas' group compared to the del Nido group after surgery (2.94+/-0.9 vs. 2.46+/-0.61 log10 pg/mL, respectively; p=0.039).
Increased levels of IL-6, IFN-gamma (显示 IFNG 抗体), and IL-10 (显示 IL10 抗体) might be useful as diagnostic biomarkers for gastric cancer; however, this needs to be confirmed with larger number of patients and with control groups other than blood donors, properly age paired.
Overexpression of IL-6 in depression is thought to be a factor associated with bad prognosis and worse major depressive disorder course. (Review)
The findings of the present study demonstrate that IL6 may promote migration in vitro via the classic and transsignaling pathways by inducing epithelialmesenchymal transition in ACP cell cultures.
Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8 (显示 IL8 抗体), MCP-1 (显示 CCL2 抗体) and COX-2 (显示 COX2 抗体) inflammation by modulating NF-kappaB (显示 NFKB1 抗体) signaling pathway in keratinocytes.
these data show that suggest that hepatic IL-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation
Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8 (显示 IL8 抗体), MCP-1 (显示 CPT1B 抗体) and COX-2 (显示 COX2 抗体) inflammation by modulating NF-kappaB (显示 NFKB1 抗体) signaling pathway in mouse skin.
By comparing wild type (WT) animals with genetically modified (TG) mice in which central IL-6 trans-signaling was blocked, study showed that central IL-6 trans-signaling modulates basal synaptic transmission as well as seizure excitability. Increases in both mEPSC and sEPSC frequency suggests that the presynaptic component of excitatory synapses undergo an enhanced development in TG vs.WT animals.
Taken together, the results of our present study indicated that DHCE could inhibit cellular proliferation and induce cell apoptosis in myeloma cells mediated through different mechanisms, possibly through inhibiting the IL-6/STAT3 and ERK1/2 pathways. And it may provide a new therapeutic option for MM patients.
In a double-hit murine model of ARDS, IL-6 deficient mice experienced more severe bronchoalveolar cellular inflammation as compared to wild-type littermates. Furthermore, IL-6 deficiency caused marked acute pulmonary hypertension, which may be, at least partially, due to vasoactive mechanisms. A dysregulation of nitric oxide synthase (显示 NOS 抗体) may account for this observation, a hypothesis that will need to be investigated in futur
Data (including data from studies using knockout mice) suggest that early initiation of endometriosis is predominantly dependent on immune system; cross-talk occurs between Esr1 (显示 ESR1 抗体) and Il6 pathways during early initiation of endometriosis lesion development; estradiol stimulation of Esr1 (显示 ESR1 抗体) appears to play minor role in early lesion development. (Esr1 (显示 ESR1 抗体) = estrogen receptor alpha (显示 ESR1 抗体); Il6 = interleukin 6)
Results show that interleukin 6 (IL6) promotes oval cell proliferation and liver regeneration, while tumor necrosis factor alpha (TNFalpha (显示 TNF 抗体)) and TNF (显示 TNF 抗体) receptor-1(TNFR1 (显示 TNFRSF1A 抗体)) do not affect this process.
IL-6 role in the bone corticalization
thrombin (显示 F2 抗体) is increased in a mouse model of cancer cachexia in a partially interleukin-6 dependent manner
Mild heat shock increased the production of inflammatory cytokines, IL-1beta (显示 IL1B 抗体) and IL-6 in rabbit cornea cells.
These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.
IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (显示 WNT2 抗体) signaling pathway transactivator beta-catenin (显示 CTNNB1 抗体), induced expression of inhibitors of the Wnt (显示 WNT2 抗体) pathway, and increased expression of GDF-5 (显示 GDF5 抗体).
study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (显示 ADORA2B 抗体) activation and that this effect can be modulated by A2AAR (显示 ADORA2A 抗体)
Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.
Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.
Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (显示 IL10 抗体) alone, were useful diagnostic indices of sepsis in equine neonates.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (显示 IL10 抗体) and TNF-alpha (显示 TNF 抗体), in horses with recurrent airway obstruction during exacerbation and in remission is reported.
The role of IL-6 and its signaling pathway in enhancing colonic proliferation.Il-6 is a key regulator of chronic intestinal inflammation.
we showed that IL-6 did not directly promote the proliferation of theca interna cells.
Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (显示 HIF1A 抗体)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (显示 TGFB1 抗体), IL-10 (显示 IL10 抗体), and IL-6 in ovarian follicles are reported.
Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (显示 STAT3 抗体) (signal transducer/activator of transcription (显示 STAT1 抗体) 3) signaling pathway (including up-regulation of STAT3 (显示 STAT3 抗体) expression/phosphorylation).
LIF (显示 LIF 抗体) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.
INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.
IL-6 was low or undetectable in Boar seminal plasma.
interleukin-6, endothelin ET-1 (显示 EDN1 抗体), and apoptotic Bak (显示 BAK1 抗体) and Bcl-XL (显示 BCL2L1 抗体) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Data show that all five molecules, BNP (显示 BNC2 抗体), ICAM-1 (显示 ICAM1 抗体), TNF-alpha (显示 TNF 抗体), VCAM-1 (显示 VCAM1 抗体) and IL-6, quickly and reliably signaled adverse interactions.
STA3 (显示 ARHGEF3 抗体) facilitates TLR4 (显示 TLR4 抗体)-dependent IL-6 and IL-8 (显示 IL8 抗体) production via IL-6 receptor-positive feedback in endometrial cells.
when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.
The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 抗体) and PTGS2 (显示 PTGS2 抗体), and decreased the expression of SOD2 (显示 SOD2 抗体), GPX3 (显示 GPX3 抗体), DAB2 (显示 DAB2 抗体), and NR3C1 (显示 NR3C1 抗体). TNF (显示 TNF 抗体) and IL6 levels were also decreased while those of NAMPT (显示 NAMPT 抗体) were unaffected.
Testicular IL-1 alpha (显示 IL1A 抗体) and IL-1 beta (显示 IL1B 抗体) concentrations were highest in the early post-natal period; however, IL-1 (显示 IL1A 抗体) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.
The results showed that the expression of TNF-alpha (显示 TNF 抗体), iNOS (显示 NOS2 抗体), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (显示 IL12A 抗体) was unaffected.[IL-6, IL-12 (显示 IL12A 抗体)]
results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (显示 IFNAR1 抗体) (sIL (显示 STIL 抗体)-6R), induces activation of JAK1 (显示 JAK1 抗体), JAK2 (显示 JAK2 抗体), and STAT1 (显示 STAT1 抗体)/STAT3 (显示 STAT3 抗体) proteins in bovine articular chondrocytes.
Mechanical injury potentiates the catabolic effects of TNFalpha (显示 TNF 抗体) and IL-6/sIL (显示 STIL 抗体)-6R in causing proteoglycan (显示 Vcan 抗体) degradation in human and bovine cartilage.
Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.
IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.
in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout
found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (显示 KRT12 抗体)), are potent inducers of IL-1beta (显示 IL1B 抗体) and IL-6 gene expression and were equal to, or more potent than, crude LPS (显示 IRF6 抗体).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
B-cell differentiation factor
, B-cell stimulatory factor 2
, CTL differentiation factor
, hybridoma growth factor
, interferon beta-2
, interleukin BSF-2
, B-cell hybridoma growth factor
, interleukin HP-1
, Interleukin 6 (interferon, beta 2)
, interleukin-6 protein
, interleukin 6 (interferon, beta 2)