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抗Human GNRH1 抗体:
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抗Rat (Rattus) GNRH1 抗体:
Atlantic Hagfish (Myxine glutinosa) Polyclonal GNRH1 Primary Antibody for IEM, ICC - ABIN617888
Masucci, DAniello, Iela, Ciarcia, Rastogi: Immunohistochemical demonstration of the presence and localization of diverse molecular forms of gonadotropin-releasing hormone in the lizard (Podarcis s. sicula) brain. in General and comparative endocrinology 1992
Show all 76 Pubmed References
Goat Polyclonal GNRH1 Primary Antibody for IF (cc), IF (p) - ABIN668841
Liu, Chang, Sun, Zhu, Pu, Zhu, Wang, Xu: Ultrasound-mediated destruction of LHRHa-targeted and paclitaxel-loaded lipid microbubbles induces proliferation inhibition and apoptosis in ovarian cancer cells. in Molecular pharmaceutics 2014
Mouse (Murine) Polyclonal GNRH1 Primary Antibody for IF, IHC - ABIN4315269
Hoffmann, Trang, Gong, Kimura, Pandolfi, Mellon: Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2016
High expression of LHRH is associated with ovarian cancer.
Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb (显示 FSHB 抗体) gene sensitivity to gonadotropin-releasing hormone pulse frequency
GNRH (and GNRHR (显示 GNRHR 抗体)) are expressed in trophoblast cell populations and fallopian tube epithelium at tubal ectopic pregnancy sites.
High LHRH expression is associated with sarcomas of bone and soft tissue.
GnRH regulates trophoblast invasion via RUNX2 (显示 RUNX2 抗体)-mediated MMP2 (显示 MMP2 抗体)/MMP9 (显示 MMP9 抗体) expression.
our results showed that GnRH participates in the self-renewal capacity and stemness maintenance of LCSLCs by upregulating the JNK signaling pathway, and GnRH may be useful as an alternative lung cancer stem-like cells therapy.
Melatonin affects the secretion of GnRH, LH and testosterone, improves sperm quality thereby regulating the testicular development and male reproduction. (Review)
Data suggest differences in regulation of expression of PEDF (显示 SERPINF1 抗体) (up-regulation) vs. VEGF (显示 VEGFA 抗体) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH/GNRHR (显示 GNRHR 抗体) agonists rather than hCG (显示 CGA 抗体).
No abnormalities were found in the patient group for the PROKR2 (显示 PROKR2 抗体) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes
Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice.
Data (including data from studies in transgenic mice) suggest that Crh alters Gnrh neuron activity and that estradiol is required for Crh to exert both stimulatory and inhibitory effects on Gnrh neurons. (Crh = corticotropin-releasing hormone; Gnrh = gonadotropin releasing hormone)
Data suggest that expression of Rps6ka5 (显示 RPS6KA5 抗体) in gonadotroph cell line is up-regulated by GnRH signaling and is required for Cga (显示 CGA 抗体) expression; GnRH-activates Rps6ka5 (显示 RPS6KA5 抗体) targets at the first nucleosome just downstream from the transcriptional start site. (Rps6ka5 (显示 RPS6KA5 抗体)= mitogen and stress-activated protein kinase 1 (显示 RPS6KA5 抗体); GnRH = gonadotropin-releasing hormone; Cga (显示 CGA 抗体) = gonadotropin alpha subunit (显示 POLG 抗体))
The studies in this manuscript describe specific histone modifications on the enhancer and promoter of the mouse GnRH (mGnRH) gene induced by kisspeptin in GnRH neuronal cell lines.
Nesfatin-1 increased Gnrh expression in hypothalamic and pituitary cells.
GnRH-E1 RNA is an inducer of Gnrh1 gene expression that may play an important role in the development and maturation of GnRH neurons
tet2 activity in GnRH neurons has influence over the neuroendocrine control of male reproductive function
Neurons in the hypothalamus produce Kiss1 and can synchronize their activity and activate GnRH neurons thus coordinating reproduction and fertility.
GnRH stimulated the secretion of the VGF (显示 VGF 抗体)-derived peptide NERP1 (显示 VGF 抗体). NERP1 (显示 VGF 抗体) caused a concentration-dependent decrease in Fshb (显示 FSHB 抗体) gene induction.
DHA and palmitate increase Gnrh enhancer-derived RNA levels.
findings suggest that GnRH is necessary for constitutive ANXA5 (显示 ANXA5 抗体) expression in the pituitary gland, not only in gonadotropes but also in other pituitary gland cell types
Guinea pig GnRH is predominantly present in the brain and has a lower in vivo luteinizaing hormone (LH)-releasing activity than Gnrh of the rat.
findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion
Posterior hypothalamic lesion animals had elevated LHRH levels and higher evening glutamate (显示 GRIN2C 抗体) levels after lesions, whereas LHRH changes did not occur in sham/controls until later.
Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30 (显示 GPER 抗体).
These results suggest that social hierarchy regulates the expression of GnRH1, GnRH3, and Kiss1 (显示 KISS1 抗体) without affecting 11-ketotestosterone level in male medaka.
Study detected several subpopulations of GnRH1 and GnRH3 neurons classified by their projection and distribution patterns using gnrh1:EGFP medaka and gnrh3:EGFP medaka
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene.
GnRH-associated peptide 1
, gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)
, luliberin I
, progonadoliberin I
, prolactin release-inhibiting factor
, gonadotropin releasing hormone 2
, luteinizing hormone-releasing hormone I
, gonadotropin releasing hormone 1
, luteinizing hormone-releasing hormone
, chicken gonadotrophin releasing hormone-I
, gonadotrophin-releasing hormone I
, gonadotropin-releasing hormone associated peptide
, progonadoliberin-1 preproprotein
, Progonadoliberin I
, luliberin i
, luteinizing hormone
, luteinizing-releasing hormone
, Medaka-type gonadotropin-releasing hormone
, gonadotropin-releasing hormone
, medaka-type gonadotropin-releasing hormone
, gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)