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|抗原||Calcitonin-Related Polypeptide alpha (CALCA) 抗体|
|适用||人, 小鼠, 大鼠 其他选择|
|标记||This CGRP antibody is un-conjugated 其他选择|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|Supplier||Log in to see|
CGRP抗体详情CGRP目标详情 使用细节 贮存及处理 References for anti-CGRP antibody (ABIN115755) 图像
|特异性||This antibody reacts with Calcitonin gene-related peptide (CGRP). Absoprtion with 10-100 μg CGRP per ml diluted antiserum abolishes the staining while Calcitonin does not. It does not cross-react with Amylin (IAPP).|
|免疫原||Synthetic Calcitonin Gene Related Peptide (Peninsula), conjugated to BSA.|
|Plasmids, Primers & others|
CGRP目标详情CGRP抗体详情 使用细节 贮存及处理 References for anti-CGRP antibody (ABIN115755) 图像 回页首
|别名||CGRP / CALCA (CALCA Antibody 摘要)|
|背景||The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I|
|途径||Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour|
使用细节CGRP抗体详情 CGRP目标详情 贮存及处理 References for anti-CGRP antibody (ABIN115755) 图像 回页首
Immunohistochemistry on Paraffin Embedded or Frozen Tissue Sections. Immunofluorescence Microscopy: Dilute 1/800-1/1200 Using FITC with overnightincubation at 2-8 °C. Recommended Positive Control: frozen sections of rat colon.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
贮存及处理CGRP抗体详情 CGRP目标详情 使用细节 References for anti-CGRP antibody (ABIN115755) 图像 回页首
|溶解方式||Dissolve the antiserum in 50-100 μL distilled water and dilute further in 0.1M PBS with 1 % BSA and 0.09 % Sodium Azide.|
|注意事项||This product is photosensitive and should be protected from light|
|储存方法||Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!|
References for anti-CGRP antibody (ABIN115755)CGRP抗体详情 CGRP目标详情 使用细节 贮存及处理 图像 回页首
Veres, Shevchenko, Krasteva, Spies, Prenzler, Rochlitzer, Tschernig, Krug, Kummer, Braun: "Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation." in: The American journal of pathology, Vol. 174, Issue 3, pp. 808-17, 2009
Schulze, Witt, Fink, Hofer, Funk: "Immunohistochemical detection of human skin nerve fibers." in: Acta histochemica, Vol. 99, Issue 3, pp. 301-9, 1997
Mulder, Lindh, Ekblad, Westermark, Sundler: "Islet amyloid polypeptide is expressed in endocrine cells of the gastric mucosa in the rat and mouse." in: Gastroenterology, Vol. 107, Issue 3, pp. 712-9, 1994