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Human BNP Protein expressed in Escherichia coli (E. coli) - ABIN987787
Lu, Fu, Chen, Lu, Yao, Shen, Gu: Multiplex detection of B-type natriuretic peptide, cardiac troponin I and C-reactive protein with photonic suspension array. in PLoS ONE 2012
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Mouse (Murine) BNP Protein expressed in Escherichia coli (E. coli) - ABIN1079003
Furrer, Eisele, Schmidt, Beer, Handschin: Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP. in Scientific reports 2017
CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals
ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.
Up-regulation of BNP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a in failing myocardium are observed in a porcine model of tachycardia.
Data show that all five molecules, BNP, ICAM-1 (显示 ICAM1 蛋白), TNF-alpha (显示 TNF 蛋白), VCAM-1 (显示 VCAM1 蛋白) and IL-6 (显示 IL6 蛋白), quickly and reliably signaled adverse interactions.
identification and characterization of a novel alternatively spliced variant of porcine and human NPPB resulting from exon 2 skipping
Arial natriuretic factor (ANF (显示 HESX1 蛋白)) and N-terminal proANF may be better suited than brain natriuretic peptide as markers of cardiac preload during the development and treatment of acute heart failure.
Regional differences in BNP and CNP expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
These results suggested that the papillary tip express a substance that can stimulate BNP production and secretion from cardiomyocytes.
This study provides the first evidence of the ability of IL-18 (显示 IL18 蛋白) to induce B-type natriuretic peptide synthesis in vitro and outlines the relationship between the two molecules in acute HF patients with an ongoing inflammatory status.
The present study provides a novel insight into the potential underlying mechanisms of telmisartan-induced inhibition of cardiomyocyte hypertrophy, which involves inhibition of NFAT activation, nuclear translocation and the ANP/BNP cascade.
Data suggest that the negative inhibition of P2X3R activity by the BNP/NPR-A (显示 NPR1 蛋白) pathway results in a decreased P2X3R-mediated excitability of trigeminal neurons in wildetype cultures. In familial hemiplegic migraine type-1 model cultures, however, lack of efficient P2X3Rs downregulation contributes to the neuronal hyperexcitability phenotype.
we have validated a novel gene, Myh14, as a negative regulator of ISO-induced left ventricular mass hypertrophy in an in vivo mouse model and demonstrated the up-regulation of immediate early gene Myc, fetal gene Nppb, and fibrosis gene Lgals3 in ISO-treated Myh14 deficient hearts compared to controls.
P2X3 (显示 P2RX3 蛋白) receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide and facilitatory calcitonin gene-related peptide (显示 CALCA 蛋白) that both operate via complex intracellular signaling.
mouse trigeminal neurons endogenous BNP acts on NPR-A (显示 NPR1 蛋白) receptors to determine constitutive depression of P2X3 (显示 P2RX3 蛋白) receptor function. Tonic inhibition of P2X3 (显示 P2RX3 蛋白) receptor activity by BNP/NPR-A (显示 NPR1 蛋白)/PKG (显示 PRKG1 蛋白) pathways occurs via two distinct mechanisms: P2X3 (显示 P2RX3 蛋白) serine phosphorylation and receptor redistribution to non-raft membrane compartments
The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 and ENaCalpha in obstructive kidney disease, possibly via iNOS-derived nitric oxide and BNP.
Data (including data from studies in knockout mice) suggest expression of ANP (显示 NPPA 蛋白)/BNP/GC-A (显示 GUCA1A 蛋白) (atrial natriuretic peptide (显示 NPPA 蛋白), brain natriuretic peptide, and guanylyl cyclase-A (显示 NPR1 蛋白)) is important in embryonic neovascularization and organogenesis.
Goalpha plays a role in ANF sorting during intracellular vectorial transport and with the presence of a mechanism that preserves the molar relationship between cellular ANF and BNP.
hormone produced primarily by the atrium and ventricle of the heart
brain natriuretic peptide
, gamma-brain natriuretic peptide
, natriuretic peptides B
, Brain natriuretic factor
, natriuretic peptide precursor B
, natriuretic peptide precursor type B
, Gamma-brain natriuretic peptide