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LIMK2 抗体

(LIM Domain Kinase 2 (LIMK2))
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
LIMK2 抗体  (pSer283) LIMK2 抗体  (pSer283) LIMK2 抗体 (pSer283) (ABIN6256239)

LIMK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

LIMK2 抗体  (AA 1-686) LIMK2 抗体  (AA 1-686) LIMK2 抗体 (AA 1-686) (ABIN561676)

LIMK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H2-E11 unconjugated

LIMK2 抗体  (pThr505) LIMK2 抗体  (pThr505) LIMK2 抗体 (pThr505) (ABIN7138860)

LIMK2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

LIMK2 抗体 by Grade

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LIMK2 抗体 by 适用

Find LIMK2 抗体 for a variety of species such as anti-Human LIMK2, anti-Mouse LIMK2, anti-Rat LIMK2. The species listed below are among those available. Click on a link to go to the corresponding products.

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LIMK2 抗体 by 抗原表位

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LIMK2 抗体 by 克隆形成能力

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LIMK2 抗体 by 克隆

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LIMK2 抗体 by 标记

Find LIMK2 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LIMK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (10)
Cat. No. ABIN6256239
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN561676
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7138860
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN517526
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2856539
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7180040
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7158358
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN2566025
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN5539550
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6143230
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7296190
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN1533779
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN517524
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3185386
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF
Validations
  • (1)
Cat. No. ABIN3182061
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our LIMK2 抗体

Kim, Ryu, Kim, Kang: "LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission." in: Cell death and differentiation, Vol. 21, Issue 7, pp. 1036-49, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Soosairajah, Maiti, Wiggan, Sarmiere, Moussi, Sarcevic, Sampath, Bamburg, Bernard: "Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin." in: The EMBO journal, Vol. 24, Issue 3, pp. 473-86, (2005) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: "Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop." in: The Journal of biological chemistry, Vol. 275, Issue 5, pp. 3577-82, (2000) (PubMed).

Jhiang: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).

Edwards, Sanders, Bokoch, Gill: "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics." in: Nature cell biology, Vol. 1, Issue 5, pp. 253-9, (1999) (PubMed).

Aliases for LIMK2 抗体

LIM domain kinase 2 L homeolog (limk2.L) 抗体
LIM domain kinase 2 (limk2) 抗体
LIM domain kinase 2 (LIMK2) 抗体
LIM domain kinase 2 (Limk2) 抗体
LIM motif-containing protein kinase 2 (Limk2) 抗体
9430059K01 抗体
A930024P04Rik 抗体
C85310 抗体
LIMK 抗体
LIMK2 抗体
Limk2a 抗体
Limk2b 抗体
Link2 抗体
wu:fa97c09 抗体
wu:fk73e11 抗体
xlimk2 抗体
zgc:91990 抗体
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