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TYK2 抗体

(Tyrosine Kinase 2 (TYK2))
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008].
TYK2 抗体  (AA 276-375) TYK2 抗体  (AA 276-375) TYK2 抗体 (AA 276-375) (ABIN563303)

TYK2 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 6G12 unconjugated

TYK2 抗体  (AA 276-375) TYK2 抗体  (AA 276-375) TYK2 抗体 (AA 276-375) (ABIN521186)

TYK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6H1 unconjugated

TYK2 抗体  (AA 750-850) TYK2 抗体  (AA 750-850) TYK2 抗体 (AA 750-850) (ABIN3022988)

TYK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

TYK2 抗体 by 适用

Find TYK2 抗体 for a variety of species such as anti-Human TYK2, anti-Mouse TYK2, anti-Rat TYK2. The species listed below are among those available. Click on a link to go to the corresponding products.

TYK2 抗体 by 应用范围

Find TYK2 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

TYK2 抗体 by 抗体来源

Find TYK2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TYK2 抗体 by 抗原表位

Find TYK2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TYK2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TYK2 抗体. Click on a link to go to the corresponding products.

TYK2 抗体 by 克隆

Find TYK2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TYK2 抗体 by 标记

Find TYK2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TYK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), IP
Validations
  • (7)
Cat. No. ABIN563303
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN521186
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN3022988
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN746318
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7161691
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN521185
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265820
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN2855727
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN969448
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN1533032
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN719591
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN7433834
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138907
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (1)
Cat. No. ABIN3187388
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6136278
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TYK2 抗体

Forsström, Axnäs, Stengele, Bühler, Albert, Richmond, Hu, Nilsson, Hudson, Rockberg, Uhlen: "Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 6, pp. 1585-97, (2014) (PubMed).

Shaw, Freeman, Scott, Fox, Bzik, Belkaid, Yap: "Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7263-71, (2006) (PubMed).

Zheng, Hu, Quinn, Wang: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, (2005) (PubMed).

Stoiber, Kovacic, Schuster, Schellack, Karaghiosoff, Kreibich, Weisz, Artwohl, Kleine, Muller, Baumgartner-Parzer, Ghysdael, Freissmuth, Sexl: "TYK2 is a key regulator of the surveillance of B lymphoid tumors." in: The Journal of clinical investigation, Vol. 114, Issue 11, pp. 1650-8, (2004) (PubMed).

Seto, Nakajima, Suto, Shimoda, Saito, Nakayama, Iwamoto: "Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1077-83, (2003) (PubMed).

Ragimbeau, Dondi, Alcover, Eid, Uzé, Pellegrini: "The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression." in: The EMBO journal, Vol. 22, Issue 3, pp. 537-47, (2003) (PubMed).

Kiian, Tkachuk, Haller, Dumler: "Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway." in: Thrombosis and haemostasis, Vol. 89, Issue 5, pp. 904-14, (2003) (PubMed).

Lukashova, Chen, Duhé, Rola-Pleszczynski, Stanková: "Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3794-800, (2003) (PubMed).

Blesofsky, Mowen, Arduini, Baker, Murphy, Bowtell, David: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, (2001) (PubMed).

Masuda, Matsuguchi, Yamaki, Hayakawa, Kubo, LaRochelle, Yoshikai: "Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells." in: The Journal of biological chemistry, Vol. 275, Issue 38, pp. 29331-7, (2000) (PubMed).

Aliases for TYK2 抗体

tyrosine kinase 2 (TYK2) 抗体
tyrosine kinase 2 (Tyk2) 抗体
JTK1 抗体
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