SOCS3 抗体
(Suppressor of Cytokine Signaling 3 (SOCS3))
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
SOCS3 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
SOCS3 抗体 by Grade
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SOCS3 抗体 by 适用
Find SOCS3 抗体 for a variety of species such as anti-Human SOCS3, anti-Mouse SOCS3, anti-Rat SOCS3. The species listed below are among those available. Click on a link to go to the corresponding products.
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SOCS3 抗体 by 克隆形成能力
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SOCS3 抗体 by 克隆
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SOCS3 抗体 by 标记
Find SOCS3 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Validations
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Quantity
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Datasheet
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Latest Publications for our SOCS3 抗体
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." in: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).: "MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3." in: Oncotarget, Vol. 8, Issue 54, pp. 92801-92814, (2017) (PubMed).
: "SOCS3 blocks HIF-1? expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 83-92, (2015) (PubMed).
: "In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 308, Issue 6, pp. R543-55, (2015) (PubMed).
: "Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 5006-17, (2015) (PubMed).
: "Dynamic expression of the suppressor of cytokine signaling-3 and cytokines in the cerebral basilar artery of rats with subarachnoid hemorrhage, and the effect of acetylcholine." in: Acta neurochirurgica, Vol. 156, Issue 5, pp. 941-9; discussion 949, (2014) (PubMed).
: "Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats." in: Physiology & behavior, Vol. 138, pp. 208-18, (2014) (PubMed).
: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, (2013) (PubMed).
: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, (2013) (PubMed).
: "Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 33, Issue 5, pp. 615-22, (2013) (PubMed).
Aliases for SOCS3 抗体
suppressor of cytokine signaling 3a (socs3a) 抗体suppressor of cytokine signaling 3 S homeolog (socs3.S) 抗体
suppressor of cytokine signaling 3 (socs3) 抗体
suppressor of cytokine signaling 3 L homeolog (socs3.L) 抗体
suppressor of cytokine signaling 3 (SOCS3) 抗体
suppressor of cytokine signaling 3a (socs3) 抗体
suppressor of cytokine signaling 3 (Socs3) 抗体
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