EIF2S1 抗体
(Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2\; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3\; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010].
recommended
EIF2S1 适用: 人 WB, IF, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated
recommended
EIF2S1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
recommended
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EIF2S1 抗体 by 克隆形成能力
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Popular EIF2S1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, ELISA, RNAi
Validations
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Cat. No.
ABIN560711
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ELISA, ICC
Validations
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Cat. No.
ABIN6255389
Quantity
100 μL
Datasheet
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Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p)
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Cat. No.
ABIN1497972
Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
ABIN6261472
Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN7127690
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN7138634
Quantity
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Datasheet
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Cat. No.
ABIN7138638
Quantity
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Datasheet
Datasheet
Reactivity
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IHC, IF
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Cat. No.
ABIN7254993
Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB, FACS
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Cat. No.
ABIN1497970
Quantity
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Datasheet
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IHC, IF, ELISA
Validations
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Cat. No.
ABIN7152131
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Goat, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
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WB, IHC, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN657392
Quantity
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Datasheet
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Reactivity
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Application
WB, IHC, IP, ICC
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Cat. No.
ABIN7445393
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN5577154
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN5577156
Quantity
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Datasheet
Datasheet
Latest Publications for our EIF2S1 抗体
: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
: "Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an ..." in: Molecular cancer, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." in: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).
: "The spliceosome is a therapeutic vulnerability in MYC-driven cancer. ..." in: Nature, Vol. 525, Issue 7569, pp. 384-8, (2015) (PubMed).
: "IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR." in: RNA (New York, N.Y.), Vol. 15, Issue 8, pp. 1528-42, (2009) (PubMed).
: "Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells." in: Molecular and cellular biology, Vol. 26, Issue 10, pp. 3955-65, (2006) (PubMed).
: "Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 291, Issue 5, pp. L983-92, (2006) (PubMed).
: "Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20457-60, (2003) (PubMed).
: "Identification and characterization of a novel transcription factor participating in the expression of eukaryotic initiation factor 2 alpha." in: The Journal of biological chemistry, Vol. 264, Issue 34, pp. 20372-84, (1990) (PubMed).
Aliases for EIF2S1 抗体
eukaryotic translation initiation factor 2 subunit alpha (EIF2S1) 抗体eukaryotic translation initiation factor 2, subunit 1 alpha a (eif2s1a) 抗体
eukaryotic translation initiation factor 2 subunit alpha (Eif2s1) 抗体
eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1) 抗体
eukaryotic translation initiation factor 2 subunit alpha (eif2s1) 抗体
eukaryotic translation initiation factor 2 alpha subunit (LOC693063) 抗体
eukaryotic translation initiation factor 2 alpha subunit (CNI00230) 抗体
eukaryotic translation initiation factor 2 alpha subunit (THAPSDRAFT_105) 抗体
Eukaryotic translation initiation factor 2 subunit 1 (if2a) 抗体
eukaryotic translation initiation factor 2 subunit alpha L homeolog (eif2s1.L) 抗体
eukaryotic translation Initiation Factor 2alpha (eIF-2alpha) 抗体
35kDa 抗体
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2410026C18Rik 抗体
CG9946 抗体
deIF2alpha 抗体
Dmel\\CG9946 抗体
EIF-2 抗体
eIF-2 抗体
eIF-2 a 抗体
eIF-2 alpha 抗体
EIF-2A 抗体
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eiF-2alpha 抗体
EIF2 抗体
eIF2 alpha 抗体
eIF2-alpha 抗体
EIF2A 抗体
Eif2a 抗体
eif2a 抗体
eIF2a 抗体
eIF2alpha 抗体
Eif2alpha 抗体
Eif2s1 抗体
eif2s1l 抗体
elF2alpha 抗体
fb36a08 抗体
IF2A_DROME 抗体
l(1)14Cf 抗体
l(1)19-153 抗体
M(1)8e3-10 抗体
M(1)14C 抗体
M(1)19-153 抗体
wu:fb36a08 抗体
zgc:56510 抗体
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