anti-兔 GLI1 抗体 for Western Blotting

Recommended GLI1 Antibody (supplied by: Log in to see )

抗原
Zinc Finger Protein GLI1 (GLI1) 抗体
  • GLI
  • Gli
  • Gli-1
  • gli1.1
  • AV235269
  • Zfp-5
  • Zfp5
  • GLI family zinc finger 1
  • GLI family zinc finger 1 S homeolog
  • GLI-Kruppel family member GLI1
  • GLI1
  • Gli1
  • gli1.S
  • gli1
抗原表位
C-Term
42
15
15
13
13
13
12
6
6
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
180
66
27
5
3
3
3
3
2
2
2
1
宿主

112
70
2
1
1
克隆类型
多克隆
标记
This GLI1 antibody is un-conjugated
6
6
6
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
155
49
48
44
24
22
17
13
13
4
3
2
1
1
选项
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产品编号 ABIN2779593
$ 229.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1084251 ABIN2792532 WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN202974 WB Rabbit IgG AA 1007-1056 Log in to see Polyclonal 0
1 ABIN202973 WB Rabbit IgG N-Term Log in to see Polyclonal 0

General

抗原 Zinc Finger Protein GLI1 (GLI1) 抗体
抗原表位 C-Term
(42), (15), (15), (13), (13), (13), (12), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
(180), (66), (27), (5), (3), (3), (3), (3), (2), (2), (2), (1)
宿主
(112), (70), (2), (1), (1)
克隆类型
多克隆
标记 This GLI1 antibody is un-conjugated
(6), (6), (6), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(155), (49), (48), (44), (24), (22), (17), (13), (13), (4), (3), (2), (1), (1)
Pubmed 9个引用可参考
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GLI1抗体详情

GLI1目标详情 使用细节 贮存及处理 References for anti-GLI1 antibody (ABIN2779593) 图像
序列 TNPSCGHPEV GRLGGGPALY PPPEGQVCNP LDSLDLDNTQ LDFVAILDEP
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against GLI1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human GLI1
Plasmids, Primers & others

GLI1目标详情

GLI1抗体详情 使用细节 贮存及处理 References for anti-GLI1 antibody (ABIN2779593) 图像 回页首
抗原
别名 GLI1 (GLI1 Antibody 摘要)
背景 GLI1 is a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined, however, it may play a role in normal development gene transcription. Mouse mutation studies indicate possible involvement in human foregut malformation.
Alias Symbols: GLI
Protein Interaction Partner: TRIM42, GCC1, PRKAA2, VHL, FEM1B, CDK4, UBC, MYC, ITCH, NUMB, SUFU, RAI1, XBP1, HDAC2, HDAC1, STK36, DYRK1A, ZIC2, ZIC1, Sin3a, Shh, SAP18, Su(fu), Pias1,
Protein Size: 1106
分子量 118 kDa
基因ID 2735
NCBI登录号 NM_005269, NP_005260
UniProt P08151
途径 Hedgehog Signaling, Dopaminergic Neurogenesis

使用细节

GLI1抗体详情 GLI1目标详情 贮存及处理 References for anti-GLI1 antibody (ABIN2779593) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 1106 AA

限制 仅限研究用

贮存及处理

GLI1抗体详情 GLI1目标详情 使用细节 References for anti-GLI1 antibody (ABIN2779593) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GLI1 antibody (ABIN2779593)

GLI1抗体详情 GLI1目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Bosco-Clément, Zhang, Chen, Zhou, Li, Mikami, Hirata, Yagui-Beltran, Lui, Do, Cheng, Tseng, Choi, Fang, Kim, Yue, Wang, Zheng, Fujii, Mann, Jablons, He: "Targeting Gli transcription activation by small molecule suppresses tumor growth." in: Oncogene, Vol. 33, Issue 16, pp. 2087-97, 2014

Pandolfi, Montagnani, Penachioni, Vinci, Olivito, Borgognoni, Stecca: "WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function." in: Oncogene, Vol. 32, Issue 40, pp. 4737-47, 2013

Iwata, Suzuki, Pelikan, Ho, Sanchez-Lara, Chai: "Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice." in: Human molecular genetics, Vol. 23, Issue 1, pp. 182-93, 2013

Ortega, Cases, Merchán, Kozyraki, Clemente, de Castro: "Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development." in: Glia, Vol. 60, Issue 6, pp. 851-66, 2012

Ferruzzi, Mennillo, De Rosa, Giordano, Rossi, Benedetti, Magrini, Pericot Mohr, Miragliotta, Magnoni, Mori, Thomas, Tunici, Bakker: "In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines." in: International journal of cancer. Journal international du cancer, Vol. 131, Issue 2, pp. E33-44, 2012

Maitah, Ali, Ahmad, Gadgeel, Sarkar: "Up-regulation of sonic hedgehog contributes to TGF-?1-induced epithelial to mesenchymal transition in NSCLC cells." in: PLoS ONE, Vol. 6, Issue 1, pp. e16068, 2011

Schiapparelli, Shahi, Enguita-Germán, Johnsen, Kogner, Lázcoz, Castresana: "Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells." in: Cancer letters, Vol. 310, Issue 2, pp. 222-31, 2011

Yoshimura, Kawate, Takeda: "Signaling through the primary cilium affects glial cell survival under a stressed environment." in: Glia, Vol. 59, Issue 2, pp. 333-44, 2010

背景

Rahnama, Shimokawa, Lauth, Finta, Kogerman, Teglund, Toftgård, Zaphiropoulos: "Inhibition of GLI1 gene activation by Patched1." in: The Biochemical journal, Vol. 394, Issue Pt 1, pp. 19-26, 2006

图像

GLI1抗体详情 GLI1目标详情 使用细节 贮存及处理 References for anti-GLI1 antibody (ABIN2779593) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibody (ABIN2779593) WB Suggested Anti-GLI1 Antibody Titration: 2.5ug/ml Positive Control: HepG2 cell l...
Western Blotting (WB) image for anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibody (ABIN2779593) WB Suggested Anti-GLI1
Antibody Titration: 1.0 µg/mL
Positive Control: ...
Western Blotting (WB) image for anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibody (ABIN2779593) Host: Rabbit Target Name: GLI1 Sample Tissue: Human Jurkat Antibody Dilution: ...
Western Blotting (WB) image for anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibody (ABIN2779593) Host: Rabbit Target Name: GLI1 Sample Type: Jurkat Whole Cell lysates Antibody ...
Western Blotting (WB) image for anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibody (ABIN2779593) Host: Rabbit Target Name: GLI1 Sample Type: HepG2 Whole Cell lysates Antibody D...