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抗Mouse (Murine) ITIH5 抗体:
抗Human ITIH5 抗体:
抗Cow (Bovine) ITIH5 抗体:
indicate an additional and specific role of this gene in the female reproductive tract, and furthermore reinforces ITIH5 as a putative candidate gene for MRKH syndrome.
ITIH5 may represent a novel modulator of TGF-beta (显示 TGFB1 抗体) superfamily signaling.
Results provide evidence that ITIH5 triggers a reprogramming of breast cancer cells through global epigenetic changes effecting DAPK1 (显示 DAPK1 抗体). ITIH5 may represent an ECM (显示 MMRN1 抗体) modulator in epithelial breast tissue mediating suppression of tumor initiating cancer cell characteristics which are thought being responsible for the metastasis of breast cancer.
Low ITIH5 expression is associated with liver metastasis in pancreatic cancer.
This is the first study so far showing a putative tumor suppressive function of ITIH5 in cervical carcinogenesis.
The current study describes a novel mechanism linking the TSG-6 (显示 TNFAIP6 抗体) transfer of the newly described HC5 (显示 PSMB1 抗体) to the HA-dependent control of cell phenotype. The interaction of HC5 (显示 PSMB1 抗体) with cell surface HA was essential for TGFbeta1 (显示 TGFB1 抗体)-dependent differentiation of fibroblasts to myofibroblasts, highlighting its importance as a novel potential therapeutic target.
ITIH5 may be a novel putative tumor suppressor gene in NSCLC with a potential molecular significance in the squamoid ADC (显示 ADC 抗体) subtype and further clinical impact for risk stratification of adenocarcinoma patients.
Hence, we can strengthen the presumption that ITIH5 may constitute a novel regulatory molecule of the human skin that could play an important role in in fl ammation via its interaction with hyaluronic acid.
ITIH5 expression is decreased in gastric cancer and that low expression of this protein is associated with poor clinical outcome.
ITIH5 is a novel putative tumor suppressor gene in colon cancer with a potential impact in the CIMP-related pathway.
Tumor-specific methylation of the three-gene panel (ITIH5, DKK3 (显示 DKK3 抗体), and RASSF1A (显示 RASSF1 抗体)) might be a valuable biomarker for the early detection of breast cancer.
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.
ITI heavy chain H5
, inter-alpha trypsin inhibitor heavy chain precursor 5
, inter-alpha-inhibitor heavy chain 5
, inter-alpha-trypsin inhibitor heavy chain H5
, inter-alpha (globulin) inhibitor H5
, inter-alpha trypsin inhibitor heavy chain 5