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PTPN11 蛋白

(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
PTPN11 Protein (AA 1-460) (GST tag) PTPN11 Protein (AA 1-460) (GST tag) PTPN11 Protein (AA 1-460) (GST tag) (ABIN1316822)

PTPN11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

PTPN11 Protein (His tag) PTPN11 Protein (His tag) PTPN11 Protein (His tag) (ABIN7197591)

PTPN11 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active

PTPN11 Protein (AA 2-597) (His tag) PTPN11 Protein (AA 2-597) (His tag) PTPN11 Protein (AA 2-597) (His tag) (ABIN3086765)

Crystallography grade PTPN11 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

PTPN11 蛋白 by Grade

Find PTPN11 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PTPN11 蛋白 by Origin

Find PTPN11 蛋白 for a variety of species such as anti-Human PTPN11, anti-Rat PTPN11, anti-Mouse PTPN11. The species listed below are among those available. Click on a link to go to the corresponding products.

PTPN11 蛋白 by Source

Here you will find PTPN11 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PTPN11 蛋白 by 蛋白类型

Here you can find PTPN11 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PTPN11 蛋白 by 应用范围

Find PTPN11 蛋白 validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PTPN11 蛋白 by 生物活性

Find PTPN11 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN11 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316822
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7197591
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086765
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133808
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505167
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397573
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7509247
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus
Validations
Cat. No. ABIN7507812
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN5855056
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730110
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6382351
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474246
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PTPN11 蛋白

Jo, Park, Lee, Ahn, Kim, Park, Choi: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).

Aliases for PTPN11 蛋白

protein tyrosine phosphatase, non-receptor type 11 (PTPN11) 蛋白
protein tyrosine phosphatase, non-receptor type 11 (Ptpn11) 蛋白
protein tyrosine phosphatase, non-receptor type 11 S homeolog (ptpn11.S) 蛋白
protein tyrosine phosphatase, non-receptor type 11, a (ptpn11a) 蛋白
protein tyrosine phosphatase, non-receptor type 11, b (ptpn11b) 蛋白
2700084A17Rik 蛋白
AW536184 蛋白
BPTP3 蛋白
bptp3 蛋白
CFC 蛋白
cfc 蛋白
fa14b09 蛋白
NS1 蛋白
ns1 蛋白
PTP-1D 蛋白
ptp-2 蛋白
PTP1D 蛋白
PTP2C 蛋白
ptp2c 蛋白
ptpn11 蛋白
ptpn11-a 蛋白
ptpn11-b 蛋白
SAP-2 蛋白
SH-PTP2 蛋白
SH-PTP3 蛋白
SHP-2 蛋白
shp-2 蛋白
SHP2 蛋白
Shp2 蛋白
shp2 蛋白
Syp 蛋白
SYP 蛋白
wu:fa14b09 蛋白
wu:fi24f03 蛋白
zgc:55388 蛋白
zgc:63553 蛋白
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