ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) 产品
(ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
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The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012].
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Featured ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Categories
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) 抗体
High quality antibodies with extensive validation data.
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7258904
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN560725
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN6140112
Quantity
100 μL
Datasheet
Datasheet
Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966469
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975056
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955527
Quantity
96 tests
Datasheet
Datasheet
Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352665
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352664
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3092443
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Products
: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." in: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).: "Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes." in: The Biochemical journal, Vol. 473, Issue 21, pp. 4027-4044, (2016) (PubMed).
: "Positive regulation of HIF-1A expression by EBV oncoprotein LMP1 in nasopharyngeal carcinoma cells." in: Cancer letters, Vol. 382, Issue 1, pp. 21-31, (2016) (PubMed).
: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." in: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).
: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).
: "Tissue-specific control of brain-enriched miR-7 biogenesis." in: Genes & development, Vol. 27, Issue 1, pp. 24-38, (2013) (PubMed).
: "Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent." in: Carcinogenesis, Vol. 34, Issue 12, pp. 2694-705, (2013) (PubMed).
: "Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition." in: Molecular cancer therapeutics, Vol. 11, Issue 5, pp. 1071-81, (2012) (PubMed).
: "The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition." in: The Journal of biological chemistry, Vol. 287, Issue 52, pp. 43639-50, (2012) (PubMed).
: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." in: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).
Synonyms and alternative names related to ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R)
ELAV like RNA binding protein 1 (ELAVL1), ELAV like RNA binding protein 1 (Elavl1), ELAV-like protein 1 (elav1), ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) (Elavl1), ELAV like RNA binding protein 1a (elavl1a), ELAV like RNA binding protein 1 L homeolog (elavl1.L), ELAV like RNA binding protein 1 S homeolog (elavl1.S), 2410055N02Rik, ELAV1, elav1, Elavl1, elavl1, elavl1-a, elavl1-b, elra, elrA, ElrA, fa25f08, fb59a02, fc60g02, Hua, hua, HUR, HuR, hur, MelG, melg, p36, W91709, wu:fa25f08, wu:fb59a02, wu:fc60g02, Xel-1, zHuAProtein level used designations for ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R)
- ELAV-like protein 1
- Hu antigen R
- embryonic lethal, abnormal vision, drosophila, homolog-like 1
- hu-antigen R
- ELAV-like 1 (Hu antigen R)
- ELAV like 1
- ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
- HU-antigen A
- elav-like generic protein
- melG
- elav-related A
- embryonic lethal, abnormal vision-related A
- etID309757.2
- 36 kDa eCPE-binding protein
- 36 kDa eCPEB
- 36 kDa embryonic-type cytoplasmic polyadenylation element-binding protein
- 36-kDa eCPE-binding protein
- 36-kDa eCPEB
- 36-kDa embryonic-type cytoplasmic polyadenylation element (CPE)-binding protein
- ELAV-like protein 1-A
- Protein ElrA-A
- ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
- ELAV-like protein 1-B
- Protein ElrA-B
- elrA
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