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PTK2B 抗体

(PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PTK2B 抗体  (pTyr402) PTK2B 抗体  (pTyr402) PTK2B 抗体 (pTyr402) (ABIN745763)

PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

PTK2B 抗体  (AA 1-1009) PTK2B 抗体  (AA 1-1009) PTK2B 抗体 (AA 1-1009) (ABIN515514)

PTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

PTK2B 抗体  (AA 682-871) PTK2B 抗体  (AA 682-871) PTK2B 抗体 (AA 682-871) (ABIN560841)

PTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated

PTK2B 抗体 by 适用

Find PTK2B 抗体 for a variety of species such as anti-Mouse PTK2B, anti-Human PTK2B, anti-Rat PTK2B. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular PTK2B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (4)
Cat. No. ABIN745763
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, PLA
Validations
  • (5)
Cat. No. ABIN515514
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (5)
Cat. No. ABIN560841
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7138999
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN6243517
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7241282
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN947856
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1500493
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (2)
Cat. No. ABIN1724705
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7180078
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7166444
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7139029
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7269745
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2752412
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN515513
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PTK2B 抗体

Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: "Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment." in: Cell reports, Vol. 18, Issue 8, pp. 1946-1957, (2017) (PubMed).

Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: "Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis." in: Bone, Vol. 74C, pp. 58-68, (2015) (PubMed).

Liu, Xu, Huang, Fei, Chen, Li, Han: "Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2." in: Cancer letters, Vol. 329, Issue 2, pp. 164-73, (2013) (PubMed).

Tomomura, Hasegawa, Suda, Sakagami, Tomomura et al.: "Serum calcium-decreasing factor, caldecrin, inhibits receptor activator of NF-?B ligand (RANKL)-mediated Ca2+ signaling and actin ring formation in mature osteoclasts via suppression of Src signaling ..." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 17963-74, (2012) (PubMed).

Anand, Cucchiarini, Terwilliger, Ganju: "The tyrosine kinase Pyk2 mediates lipopolysaccharide-induced IL-8 expression in human endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 8, pp. 5636-44, (2008) (PubMed).

Faure, Corvol, Toutant, Valjent, Hvalby, Jensen, El Messari, Corsi, Kadaré, Girault: "Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons." in: Journal of cell science, Vol. 120, Issue Pt 17, pp. 3034-44, (2007) (PubMed).

Krishnan, Sharma-Walia, Streblow, Naranatt, Chandran: "Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells." in: Journal of virology, Vol. 80, Issue 3, pp. 1167-80, (2006) (PubMed).

Ling, Sheng, Braun: "The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation." in: American journal of physiology. Cell physiology, Vol. 287, Issue 3, pp. C698-706, (2004) (PubMed).

Gluck: "Acid sensing in renal epithelial cells." in: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1696-9, (2004) (PubMed).

"Fresh concepts in dental design." in: Journal of the California Dental Association, Vol. 32, Issue 5, pp. 365-6, (2004) (PubMed).

Aliases for PTK2B 抗体

protein tyrosine kinase 2 beta (PTK2B) 抗体
PTK2 protein tyrosine kinase 2 beta (Ptk2b) 抗体
protein tyrosine kinase 2 beta (Ptk2b) 抗体
protein tyrosine kinase 2aa (ptk2aa) 抗体
CADTK 抗体
CAKB 抗体
CAKbeta 抗体
E430023O05Rik 抗体
FADK2 抗体
fak1b 抗体
FAK2 抗体
PKB 抗体
PTK 抗体
ptk2.2 抗体
ptk2b 抗体
PYK2 抗体
Pyk2 抗体
RAFTK 抗体
Raftk 抗体
si:ch1073-355e8.1 抗体
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