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The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia.
The tubule formations were dependent on microtubule interactions, and specifically controlled by Kif16b and dynein 1.
genome-wide significance in genes involved in synaptic signaling (KIF16B; p = 1.27E-08) and neurodevelopment (PAX5 (显示 PAX5 蛋白); p = 3.58E-08).
KIF16B, a kinesin-3, transports early endosomes to the plus end of microtubules in a process regulated by the small GTPase (显示 RACGAP1 蛋白) Rab5 (显示 RAB5A 蛋白) and its effector.
the stalk domain of kinesin superfamily protein 16B determines the specific somatodendritic localization of Endosomes mediated by a novel intramolecular inhibitory mechanism.
The kinesin-3 motor KIF16B/Rab14 (显示 RAB14 蛋白) complex acts in biosynthetic Golgi-to-endosome traffic of the fibroblast growth factor receptor (FGFR) during early embryonic development.
The most salient structural feature of KIF16B-PX is that two neighboring residues, L1248 and F1249, on the membrane-binding surface form a protruding hydrophobic stalk with a large solvent-accessible surface area
The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene.
chromosome 20 open reading frame 23
, kinesin family member 16B
, kinesin-like motor protein C20orf23
, inserted sequence in spleen necrosis virus vector provirus clone
, kinesin-like protein KIF16B
, chromosome 20 open reading frame 23-like
, kinesin-like protein KIF16B-like
, kinesin motor protein
, sorting nexin 23
, N-3 kinesin
, kinesin 16B