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CSK 蛋白

(C-Src tyrosine Kinase (CSK))
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
CSK Protein (AA 1-450) (GST tag) CSK Protein (AA 1-450) (GST tag) CSK Protein (AA 1-450) (GST tag) (ABIN1350517)

CSK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

CSK Protein (AA 1-450) (His-GST) CSK Protein (AA 1-450) (His-GST) CSK Protein (AA 1-450) (His-GST) (ABIN5570539)

CSK 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active

CSK Protein (AA 1-450) (His tag) CSK Protein (AA 1-450) (His tag) CSK Protein (AA 1-450) (His tag) (ABIN7122058)

CSK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

CSK 蛋白 by Grade

Find CSK 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CSK 蛋白 by Origin

Find CSK 蛋白 for a variety of species such as anti-Human CSK, anti-Mouse CSK, anti-Chicken CSK. The species listed below are among those available. Click on a link to go to the corresponding products.

CSK 蛋白 by Source

Here you will find CSK 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CSK 蛋白 by 蛋白类型

Here you can find CSK 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CSK 蛋白 by 应用范围

Find CSK 蛋白 validated for a specific application such as ELISA, WB, SDS, Func. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CSK 蛋白 by 生物活性

Find CSK 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular CSK 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1350517
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5570539
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122058
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350519
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320121
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320001
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317088
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091919
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134000
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2712578
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508887
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418323
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712579
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474579
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1618241
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CSK 蛋白

Jo, Park, Lee, Ahn, Kim, Park, Choi: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).

Aliases for CSK 蛋白

C-terminal Src kinase (CSK) 蛋白
c-src tyrosine kinase (Csk) 蛋白
C-terminal Src kinase (Csk) 蛋白
c-src tyrosine kinase (CSK) 蛋白
CSK, non-receptor tyrosine kinase (CSK) 蛋白
AW212630 蛋白
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