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抗Human Adenosine a1 Receptor 抗体:
抗Mouse (Murine) Adenosine a1 Receptor 抗体:
抗Rat (Rattus) Adenosine a1 Receptor 抗体:
Human Polyclonal Adenosine a1 Receptor Primary Antibody for FACS, ICC - ABIN4278349
Yu, Zacharia, Jackson, Apodaca: Adenosine receptor expression and function in bladder uroepithelium. in American journal of physiology. Cell physiology 2006
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Human Polyclonal Adenosine a1 Receptor Primary Antibody for WB - ABIN611319
Bowery, Brown: The cloning of GABA(B) receptors. in Nature 1997
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Cow (Bovine) Polyclonal Adenosine a1 Receptor Primary Antibody for ELISA - ABIN314251
Funakoshi, Chan, Good, Libonati, Piuhola, Chen, MacDonnell, Lee, Herrmann, Zhang, Martini, Palmer, Sanbe, Robbins, Houser, Koch, Feldman: Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. in Circulation 2006
Human Polyclonal Adenosine a1 Receptor Primary Antibody for IF (p), IHC (p) - ABIN719396
Cao, Dai, Wei, Han, Guan, Li, Liu, Xiao, Li: Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus. in Physiology & behavior 2017
Data suggest that activation of adenosine A1 receptors elicit receptor-operated Ca(2+) entry in porcine afferent arterioles, the level of which is dependent on postnatal maturation of TRPC3 channels.
mRNA for adenosine A(1), A(2A), A(2B (显示 ADRA2B 抗体)), and A(3) receptors was expressed in arterioles and venules. Protein for A(1), A(2A), and A(2B (显示 ADRA2B 抗体)), but not A(3), was detected in both microvessel types and was further demonstrated on vascular endothelial cells
Mutation in ADORA1 may be associated with early-onset parkinsonism and cognitive dysfunction.
This study showed that increased neuronal A1R expression in Rasmussen Encephalitis may be involved in prevention of seizures spread and seizures-induced damage, limitation of both seizures and inflammation atrophy in 1 cerebral hemisphere.
A1R signaling enhances A2AR (显示 ADORA2A 抗体)-mediated neurodegeneration [review]
Mutational and computational analysis of A1-AR revealed a distinct conformation of the second extracellular loop and a wider extracellular cavity with a secondary binding pocket that can accommodate orthosteric and allosteric ligands.
this study highlights a key role for extracellular loop 2 in A1AR orthosteric ligand binding and receptor activation.
Dysregulation in ADORA1/ADORA2A (显示 ADORA2A 抗体) expression was associated with glioma development.
A1R mRNA levels and A1R density in PBMCs from idiopathic normal-pressure hydrocephalus patients were significantly lower than control subjects
In postmortem human prefrontal cortex, adenosine A1 receptor is coupled preferentially, if not exclusively, to Galphai-3.
Results show that ADORA1 rs2228079 and ADORA2A (显示 ADORA2A 抗体) rs5751876 polymorphisms are associated with the risk of Gilles de la Tourette Syndrome, co-morbid disorders, and may affect the age of tics onset in Polish population.
It has the intrinsic ability to form a heteromeric complex with metabotropic glutamate (显示 GRIN1 抗体) receptor type 1 and mutually modulate signaling.
Loss of A1AR expression results in an increased susceptibility to noise-induced cochlear neural injury and hearing loss.
Expression of the SENP2 (显示 SENP2 抗体) gene was suppressed by theobromine. In vivo knockdown studies showed that AR1 (显示 TCF20 抗体) knockdown in mice attenuated the anti-adipogenic effects of theobromine in younger mice. Theobromine suppresses adipocyte differentiation and induced C/EBPbeta (显示 CEBPB 抗体) degradation by increasing its sumoylation.
The three receptor sets considered (mAChR (显示 CHRM3 抗体), AR and TrkB (显示 NTRK2 抗体) receptors) intervene in modulating the conditions of the competition between nerve endings.
Systemic inflammatory response syndrome-associated lymphopenia is initiated by A1R desensitization and adenosine-mediated inhibition of IL-15 (显示 IL15 抗体) production is part of the mechanism that accounts for the delay in leukopenia recovery in patients with severe sepsis.
Results demonstrated a significant downregulation of adenosine A1 receptors in the cortex and striatum, concomitant to striatal D2R (显示 DRD2 抗体) downregulation in iron deficient mice and rats.
Adenosine A1A receptor and adenosine A3A receptor agonists and adenosine 5'-monophosphate cause regulated hypothermia that was characterized by a drop in total energy expenditure, physical inactivity, and preference for cooler environmental temperatures, indicating a reduced body temperature set point.
over-expression of sEH (显示 EPHX2 抗体) enhances A1AR-dependent contraction and reduces KATP channel-dependent relaxation in MAs (显示 MAS1 抗体). These results suggest a possible interaction between sEH (显示 EPHX2 抗体), A1AR, and KATP channels in regulating vascular tone.
Results indicate that the adenosine A1 receptor is an important molecular component mediating hypoxic depression in adult mice and it appears to stabilize respiration of neonatal mice
The findings of this study implicated a glial-neuronal circuit, mediated by Ado (显示 ADO 抗体), neuronal AdoRA1, and glial AdK (显示 ADK 抗体) that can modulate sleep homeostasis in a manner influenced by glial metabolic state.
Adenosine A1 receptor knockout mice displayed increased depressive-like behavior.
Data suggest that that ADORA1 forms homomers/homodimers in brain cortex.
Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodeling.
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
adenosine A1 receptor
, A1 adenosine receptor
, adenosine receptor A1