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抗Rat (Rattus) LMO3 抗体:
抗Mouse (Murine) LMO3 抗体:
抗Human LMO3 抗体:
suggested that the expression levels of Lmo3 and/or Hen2 could determine the fate of stem cells by inhibiting Hes1 function during nervous system development and might be a trigger of aberrant neurogenesis in vivo
These results support a role for LMO3 in regulating behavioral responses to ethanol, potentially through its actions in the nucleus accumbens.
Gbx2 (显示 GBX2 抗体) regulates thalamocortical axon guidance by modifying the LIM (显示 PDLIM5 抗体) and Robo codes.
when tested for behavioral responses to ethanol, transgenic mice exhibited altered ethanol sedation and consumption that correlated with Lmo3 expression levels; results suggest a role for Lmo3 in ethanol-related behaviors in mice
Results suggest that all four members of the LIM (显示 PDLIM5 抗体)-only family -- LMO1 (显示 LMO1 抗体), 2, 3, and 4 -- are important regulators of distinct developmental pathways.
Data show that the calcium- and integrin-binding protein CIB (显示 CIB1 抗体) as an LMO3-binding protein, which binds via the second LIM (显示 PDLIM5 抗体) domain (LIM2 (显示 LHX2 抗体)) of LMO3.
SH3BP5 (显示 SH3BP5 抗体), LMO3, and SNAP25 (显示 SNAP25 抗体) were expressed in diffuse large B-cell lymphoma cells and associated with clinical features.
LMO3 attenuates GATA4 (显示 GATA4 抗体)-dependent, BMP2 (显示 BMP2 抗体)-mediated inflammatory endothelial activation.
MiR (显示 MLXIP 抗体)-101 decreased the expression of LMO3 by reversing the methylation status of the LMO3 promoter and by inhibiting the presence of the methylation-related histones H3K4me2 and H3K27me3 and increasing the presence of H3K9me3 and H4K20me3 on the promoter.
LMO3 as a regulator of human adipogenesis and could contribute a mechanism resulting in visceral-fat accumulation in obesity due to excess glucocorticoids.
suggest that LMO3 is a transcriptional signal transducer in NKX2-1 (显示 NKX2-1 抗体)-amplified lung adenocarcinomas
We confirmed that the expression of LMO3 in squamous cell carcinoma is regulated by DNA methylation (显示 HELLS 抗体) of its specific promoter region.
The present results suggest that a transcriptional complex of LMO3 and HEN2 (显示 NHLH2 抗体) may contribute to the genesis and malignant phenotype of neuroblastoma (显示 ARHGEF16 抗体) by inhibiting HES1 which suppresses the transactivation of Mash1 (显示 ASCL1 抗体).
LMO3 acts as a co-repressor of p53 (显示 TP53 抗体), suppressing p53 (显示 TP53 抗体)-dependent transcriptional regulation without inhibition of its DNA-binding activity.
The deregulated expression of neuronal-specific LMO3 and HEN2 (显示 NHLH2 抗体) contributes to the genesis and progression of human neuroblastoma (显示 ARHGEF16 抗体) in a lineage-specific manner.
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.
LIM domain only protein 3
, LIM domain only 3 (rhombotin-like 2)
, LIM domain only 3
, lim domain only protein 3
, neuronal-specific transcription factor DAT1
, dopamine-inducible LIM-domain transcription factor DAT1
, LIM only 3
, LIM domain only protein 1