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p21 蛋白

(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].
p21 Protein (AA 2-164) (His tag) p21 Protein (AA 2-164) (His tag) p21 Protein (AA 2-164) (His tag) (ABIN7122536)

CDKN1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

p21 Protein (AA 2-164) (His-IF2DI Tag) p21 Protein (AA 2-164) (His-IF2DI Tag) p21 Protein (AA 2-164) (His-IF2DI Tag) (ABIN7122535)

CDKN1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

p21 Protein (AA 65-164) (GST tag) p21 Protein (AA 65-164) (GST tag) p21 Protein (AA 65-164) (GST tag) (ABIN1349007)

CDKN1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

p21 蛋白 by Grade

Find p21 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

p21 蛋白 by Origin

Find p21 蛋白 for a variety of species such as anti-Human p21, anti-Mouse p21, anti-Cat p21. The species listed below are among those available. Click on a link to go to the corresponding products.

p21 蛋白 by Source

Here you will find p21 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

p21 蛋白 by 蛋白类型

Here you can find p21 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

p21 蛋白 by 应用范围

Find p21 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular p21 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122536
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122535
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349007
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349005
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091485
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133955
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2713874
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505149
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404383
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398071
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398074
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709265
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711920
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6699762
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6120577
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our p21 蛋白

Porter, Farmaki, Altilia, Schools, West, Chen, Chang, Puzyrev, Lim, Rokow-Kittell, Friedhoff, Papavassiliou, Kalurupalle, Hurteau, Shi, Baran, Gyorffy, Wentland, Broude, Kiaris, Roninson: "Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 34, pp. 13799-804, (2012) (PubMed).

Aliases for p21 蛋白

cyclin D1 (CCND1) 蛋白
cyclin dependent kinase inhibitor 1A (CDKN1A) 蛋白
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) 蛋白
cyclin-dependent kinase inhibitor 1A (Cdkn1a) 蛋白
cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L) 蛋白
cyclin-dependent kinase inhibitor 1 (cki1) 蛋白
cyclin-dependent kinase inhibitor 1A (cdkn1a) 蛋白
cyclin dependent kinase inhibitor 1A (Cdkn1a) 蛋白
KRAS proto-oncogene, GTPase (KRAS) 蛋白
CAP20 蛋白
cap20 蛋白
CCND1 蛋白
CDKI 蛋白
CDKN1 蛋白
Cdkn1 蛋白
cdkn1 蛋白
CDKN1A 蛋白
CIP1 蛋白
Cip1 蛋白
cip1 蛋白
KRAS2 蛋白
MDA-6 蛋白
mda-6 蛋白
mda6 蛋白
p16Xic2 蛋白
P21 蛋白
p21 蛋白
p21CIP1 蛋白
p21Cip1 蛋白
p21cip1 蛋白
p21ras 蛋白
p21WAF 蛋白
SDI1 蛋白
sdi1 蛋白
si:ch1073-48m5.2 蛋白
UV96 蛋白
WAF1 蛋白
Waf1 蛋白
waf1 蛋白
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