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POLK 蛋白

(Polymerase (DNA Directed) kappa (POLK))
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].
POLK 蛋白 POLK 蛋白 POLK 蛋白 (ABIN2452172)

POLK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS-PAGE (CBB staining) ELISA, WB, Func Active

POLK Protein (AA 1-472) (GST tag) POLK Protein (AA 1-472) (GST tag) POLK Protein (AA 1-472) (GST tag) (ABIN1315652)

POLK 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

POLK Protein (AA 1-560) (His tag) POLK Protein (AA 1-560) (His tag) POLK Protein (AA 1-560) (His tag) (ABIN7124513)

POLK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

POLK 蛋白 by Grade

Find POLK 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

POLK 蛋白 by Origin

Find POLK 蛋白 for a variety of species such as anti-Human POLK, anti-Mouse POLK. The species listed below are among those available. Click on a link to go to the corresponding products.

POLK 蛋白 by Source

Here you will find POLK 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

POLK 蛋白 by 蛋白类型

Here you can find POLK 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

POLK 蛋白 by 应用范围

Find POLK 蛋白 validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLK 蛋白 by 生物活性

Find POLK 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular POLK 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (3)
Cat. No. ABIN2452172
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315652
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124513
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094746
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137340
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719558
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our POLK 蛋白

Ohashi, Bebenek, Matsuda, Feaver, Gerlach, Friedberg, Ohmori, Kunkel: "Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39678-84, (2001) (PubMed).

Ohashi, Ogi, Kusumoto, Iwai, Masutani, Hanaoka, Ohmori: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).

Czerkawski, Blaxter, Wainman: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).

Aliases for POLK 蛋白

DNA polymerase kappa (POLK) 蛋白
DNA polymerase kappa (Polk) 蛋白
polymerase (DNA directed) kappa (polk) 蛋白
DNA polymerase kappa (Tb11.01.0080) 蛋白
DNA polymerase kappa (Tb11.01.0010) 蛋白
DNA polymerase kappa (Tb11.01.0020) 蛋白
DNA polymerase kappa (Tb11.01.0030) 蛋白
DNA polymerase kappa (Tb11.01.0040) 蛋白
DNA polymerase kappa (Tb11.01.0050) 蛋白
DNA polymerase kappa (Tb11.12.0001) 蛋白
DNA polymerase kappa (Tb11.12.0002) 蛋白
DNA polymerase kappa (Tb11.12.0003) 蛋白
polymerase (DNA directed), kappa (Polk) 蛋白
polymerase (DNA directed) kappa L homeolog (polk.L) 蛋白
DNA polymerase kappa (polk-1) 蛋白
DINB1 蛋白
Dinb1 蛋白
DINP 蛋白
POLK 蛋白
POLQ 蛋白
si:ch211-254o18.3 蛋白
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