POLB 抗体
(Polymerase (DNA Directed), beta (POLB))
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].
recommended
recommended
recommended
POLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
POLB 抗体 by 应用范围
Find POLB 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
POLB 抗体 by 抗体来源
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POLB 抗体 by 克隆形成能力
Find available monoclonal or polyclonal POLB 抗体. Click on a link to go to the corresponding products.
POLB 抗体 by 克隆
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Popular POLB 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
Cat. No.
ABIN3022385
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
Cat. No.
ABIN1327635
Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6264332
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7150223
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
Cat. No.
ABIN964928
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN1386139
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7184824
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN3184326
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Cat. No.
ABIN562301
Quantity
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Datasheet
Datasheet
Reactivity
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Application
IP
Validations
- (1)
Cat. No.
ABIN519018
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6741696
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (9)
Cat. No.
ABIN966876
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (9)
Cat. No.
ABIN966878
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (9)
Cat. No.
ABIN966879
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Human, Mouse, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7296630
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our POLB 抗体
: "DNA polymerase beta participates in mitochondrial DNA repair." in: Molecular and cellular biology, (2017) (PubMed).: "p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146031, (2016) (PubMed).
: "Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade." in: Biochemical pharmacology, Vol. 105, pp. 23-33, (2016) (PubMed).
: "ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli." in: DNA repair, Vol. 45, pp. 44-55, (2016) (PubMed).
: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).
: "Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 28, pp. 8602-7, (2015) (PubMed).
: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." in: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).
: "The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death." in: Nature cell biology, Vol. 12, Issue 6, pp. 563-71, (2010) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
: "A platinum agent resistance gene, POLB, is a prognostic indicator in colorectal cancer." in: Journal of surgical oncology, Vol. 100, Issue 3, pp. 261-6, (2009) (PubMed).
Aliases for POLB 抗体
polymerase (DNA directed), beta (polb) 抗体DNA polymerase beta (POLB) 抗体
DNA polymerase X family protein (polB) 抗体
polymerase (DNA directed), beta S homeolog (polb.S) 抗体
polymerase (DNA directed), beta (Polb) 抗体
DNA polymerase beta (Polb) 抗体
A430088C08Rik 抗体
DDBDRAFT_0186152 抗体
DDBDRAFT_0215784 抗体
DDBDRAFT_0232376 抗体
DDB_0186152 抗体
DDB_0215784 抗体
DDB_0232376 抗体
POLB 抗体
wu:fa97a05 抗体
zgc:109924 抗体
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