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General |
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抗原 | 8-Oxoguanine DNA Glycosylase (OGG1) 抗体 |
抗原表位 | C-Term 其他选择 |
适用 | 牛, 犬, 马, 人, 小鼠, 猪, 大鼠 其他选择 |
宿主 | 兔 其他选择 |
克隆类型 | |
标记 | This OGG1 antibody is un-conjugated 其他选择 |
应用范围 |
Western Blotting (WB)
其他选择
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Supplier | Log in to see |
OGG1抗体详情OGG1目标详情 使用细节 贮存及处理 图像 |
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Blocking Peptide | Blocking peptide for this product available: ABIN981105 |
序列 | AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW |
特异性 | Directed against isoforms 2D, 1A, 1B, 2E. |
预测反应 | Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79% |
产品特性 | This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot. |
纯化方法 | Affinity Purified |
Plasmids, Primers & others | |
OGG1目标详情OGG1抗体详情 使用细节 贮存及处理 图像 回页首 |
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抗原 | |
别名 | OGG1 (OGG1 Antibody 摘要) |
背景 |
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Alias Symbols: HMMH, HOGG1, MUTM, OGH1 Protein Interaction Partner: ERCC6, ERCC8, UBC, Ogg1, CHGB, XRCC1, PRKCA, SNRPF, Protein Size: 345 |
分子量 | 38 kDa |
基因ID | 4968 |
NCBI登录号 | NM_016829, NP_058438 |
UniProt | O15527 |
途径 | DNA Damage Repair |
使用细节OGG1抗体详情 OGG1目标详情 贮存及处理 图像 回页首 |
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应用备注 | Optimal working dilutions should be determined experimentally by the investigator. |
说明 |
Antigen size: 345 AA |
限制 | 仅限研究用 |
贮存及处理OGG1抗体详情 OGG1目标详情 使用细节 图像 回页首 |
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状态 | Liquid |
浓度 | Lot specific |
缓冲液 | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
储存液 | Sodium azide |
注意事项 | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
注意事项 | Avoid repeated freeze-thaw cycles. |
储存条件 | -20 °C |
储存方法 | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
图像OGG1抗体详情 OGG1目标详情 使用细节 贮存及处理 回页首 |
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厂商提供的图像 |