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BTBD12 抗体

(BTB (POZ) Domain Containing 12 (BTBD12))
This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011].
BTBD12 抗体  (AA 1-1151) BTBD12 抗体  (AA 1-1151) BTBD12 抗体 (AA 1-1151) (ABIN529697)

BTBD12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

BTBD12 抗体  (AA 100-149) BTBD12 抗体  (AA 100-149) BTBD12 抗体 (AA 100-149) (ABIN6746693)

BTBD12 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated

BTBD12 抗体  (AA 1784-1834) BTBD12 抗体  (AA 1784-1834) BTBD12 抗体 (AA 1784-1834) (ABIN2571811)

BTBD12 适用: 人 IP, IHC (p), IHC, IF 宿主: 兔 Polyclonal unconjugated

BTBD12 抗体 by 适用

Find BTBD12 抗体 for a variety of species such as anti-Mouse BTBD12, anti-Human BTBD12, anti-Monkey BTBD12. The species listed below are among those available. Click on a link to go to the corresponding products.

BTBD12 抗体 by 应用范围

Find BTBD12 抗体 validated for a specific application such as IF (cc), IF (p), WB, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BTBD12 抗体 by 抗体来源

Find BTBD12 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BTBD12 抗体 by 抗原表位

Find BTBD12 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BTBD12 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BTBD12 抗体. Click on a link to go to the corresponding products.

BTBD12 抗体 by 标记

Find BTBD12 抗体 with a specific conjugate such as Alexa Fluor 350, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BTBD12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN529697
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6746693
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, IHC (p), IHC, IF
Validations
  • (1)
Cat. No. ABIN2571811
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Rabbit
Application WB
Validations
  • (2)
Cat. No. ABIN2788239
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p), IHC (p), ELISA, IHC (fro), ICC
Validations
Cat. No. ABIN6989530
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC (p), ELISA, IHC (fro)
Validations
Cat. No. ABIN6982787
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6976994
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6977855
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6978716
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6979511
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6980370
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6981282
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6982254
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6983792
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6984653
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our BTBD12 抗体

Sadhukhan, Chowdhury, Ghosh, Ghosh: "Expression of Telomere-Associated Proteins is Interdependent to Stabilize Native Telomere Structure and Telomere Dysfunction by G-Quadruplex Ligand Causes TERRA Upregulation." in: Cell biochemistry and biophysics, (2017) (PubMed).

Fregoso, Emerman: "Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment." in: mBio, Vol. 7, Issue 5, (2016) (PubMed).

Wan, Yin, Horvath, Sarkar, Chen, Wu, Wan, Lu, Gu, Yu, Lue, Chang, Liu, Lei: "SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres." in: Cell reports, Vol. 4, Issue 5, pp. 861-9, (2013) (PubMed).

Salewsky, Schmiester, Schindler, Digweed, Demuth: "The nuclease hSNM1B/Apollo is linked to the Fanconi anemia pathway via its interaction with FANCP/SLX4." in: Human molecular genetics, Vol. 21, Issue 22, pp. 4948-56, (2012) (PubMed).

Holloway, Mohan, Balmus, Sun, Modzelewski, Borst, Freire, Weiss, Cohen: "Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis." in: PLoS genetics, Vol. 7, Issue 6, pp. e1002094, (2011) (PubMed).

Kim, Lach, Desetty, Hanenberg, Auerbach, Smogorzewska: "Mutations of the SLX4 gene in Fanconi anemia." in: Nature genetics, Vol. 43, Issue 2, pp. 142-6, (2011) (PubMed).

Aliases for BTBD12 抗体

SLX4 structure-specific endonuclease subunit (Slx4) 抗体
SLX4 structure-specific endonuclease subunit (SLX4) 抗体
SLX4 structure-specific endonuclease subunit homolog (SLX4) 抗体
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) (Slx4) 抗体
AI256635 抗体
AI426760 抗体
Btbd12 抗体
BTBD12 抗体
D16Bwg1016e 抗体
FANCP 抗体
MUS312 抗体
RGD1566009 抗体
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