anti-人 C1S 抗体 for Immunoassay

Recommended C1S Antibody (supplied by: Log in to see )

抗原
Complement Component 1, S Subcomponent (C1S) 抗体
  • AA959438
  • AI255193
  • AI327365
  • C1sa
  • r-gsp
  • C1S
  • complement C1s
  • complement component 1, s subcomponent 1
  • complement component 1, s subcomponent
  • complement component 1, s subcomponent L homeolog
  • complement C1s subcomponent
  • C1S
  • C1s1
  • C1s
  • c1s
  • c1s.L
  • LOC100558615
适用

135
26
25
5
2
宿主
小鼠
72
60
4
克隆类型
单克隆
标记
This C1S antibody is un-conjugated
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
应用范围
Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
72
61
38
16
15
15
13
8
6
3
3
3
2
1
1
1
1
1
1
选项
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产品编号 ABIN2191986
$ 643.71
加上运输费 $45.00

General

抗原 Complement Component 1, S Subcomponent (C1S) 抗体
适用
(135), (26), (25), (5), (2)
宿主 小鼠
(72), (60), (4)
克隆类型 (克隆位点)
单克隆   ( )
标记 This C1S antibody is un-conjugated
(4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(72), (61), (38), (16), (15), (15), (13), (8), (6), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 找到1个引用
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C1S抗体详情

C1S目标详情 使用细节 贮存及处理 References for anti-C1S antibody (ABIN2191986) 图像
过滤 0.2 μm filtered
克隆位点 M81
Plasmids, Primers & others

C1S目标详情

C1S抗体详情 使用细节 贮存及处理 References for anti-C1S antibody (ABIN2191986) 图像 回页首
抗原
别名 c1s (C1S Antibody 摘要)
背景 Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). Activated C1s is a glycosylated single-polypeptide zymogen, MW 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a. The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M81 blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.
途径 Complement System

使用细节

C1S抗体详情 C1S目标详情 贮存及处理 References for anti-C1S antibody (ABIN2191986) 图像 回页首
应用备注 For immunohistology, flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For inhibition of C4 activation by C1s dilutions have to be made according to the amounts C1s to be inactivated.
限制 仅限研究用

贮存及处理

C1S抗体详情 C1S目标详情 使用细节 References for anti-C1S antibody (ABIN2191986) 图像 回页首
缓冲液 PBS containing 0.1 % bovine serum albumin.
储存条件 4 °C
储存方法 Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
有效期 12 months

References for anti-C1S antibody (ABIN2191986)

C1S抗体详情 C1S目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Matsumoto, Nagaki, Kitamura, Kuramitsu, Nagasawa, Seya: "Probing the C4-binding site on C1s with monoclonal antibodies. Evidence for a C4/C4b-binding site on the gamma-domain." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2743-50, 1989