anti-人 C1S 抗体 for Functional Studies

Recommended C1S Antibody (supplied by: Log in to see )

抗原
Complement Component 1, S Subcomponent (C1S) 抗体
  • AA959438
  • AI255193
  • AI327365
  • C1sa
  • r-gsp
  • C1S
  • complement C1s
  • complement component 1, s subcomponent 1
  • complement component 1, s subcomponent
  • complement component 1, s subcomponent L homeolog
  • complement C1s subcomponent
  • C1S
  • C1s1
  • C1s
  • c1s
  • c1s.L
  • LOC100558615
适用

135
26
25
5
2
宿主
小鼠
72
60
4
克隆类型
单克隆
标记
This C1S antibody is un-conjugated
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
应用范围
Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
72
61
38
17
15
15
13
8
6
3
3
2
2
1
1
1
1
1
1
1
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产品编号 ABIN1105612
$ 511.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1105613 Func EIA IHC (fro) IHC (p) IP WB Mouse IgG2a activated Log in to see M241 2

General

抗原 Complement Component 1, S Subcomponent (C1S) 抗体
适用
(135), (26), (25), (5), (2)
宿主 小鼠
(72), (60), (4)
克隆类型 (克隆位点)
单克隆   ( )
标记 This C1S antibody is un-conjugated
(4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(72), (61), (38), (17), (15), (15), (13), (8), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2个引用可参考
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C1S抗体详情

C1S目标详情 使用细节 贮存及处理 References for anti-C1S antibody (ABIN1105612) 图像
特异性 Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. It blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.
交叉反应 (详细) Species reactivity (tested):Human
纯化方法 Protein G
克隆位点 M81
亚型 IgG1
Plasmids, Primers & others

C1S目标详情

C1S抗体详情 使用细节 贮存及处理 References for anti-C1S antibody (ABIN1105612) 图像 回页首
抗原
别名 C1s (C1S Antibody 摘要)
背景 Activated C1s is a glycosylated single-polypeptide zymogen, MW 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s
基因ID 716
NCBI登录号 NP_001725
UniProt P09871
途径 Complement System

使用细节

C1S抗体详情 C1S目标详情 贮存及处理 References for anti-C1S antibody (ABIN1105612) 图像 回页首
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用

贮存及处理

C1S抗体详情 C1S目标详情 使用细节 References for anti-C1S antibody (ABIN1105612) 图像 回页首
浓度 0.1 mg/mL
缓冲液 PBS, 0.1 % bovine serum albumin
储存条件 4 °C
储存方法 Store at 2 - 8 °C.

References for anti-C1S antibody (ABIN1105612)

C1S抗体详情 C1S目标详情 使用细节 贮存及处理 图像 回页首
背景

Nakagawa, Sakiyama, Tsuchida, Yamaguchi, Toyoguchi, Masuda, Moriya: "Complement C1s activation in degenerating articular cartilage of rheumatoid arthritis patients: immunohistochemical studies with an active form specific antibody." in: Annals of the rheumatic diseases, Vol. 58, Issue 3, pp. 175-81, 1999

Matsumoto, Nagaki, Kitamura, Kuramitsu, Nagasawa, Seya: "Probing the C4-binding site on C1s with monoclonal antibodies. Evidence for a C4/C4b-binding site on the gamma-domain." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2743-50, 1989