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BRD4 抗体

(Bromodomain Containing 4 (BRD4))
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
BRD4 抗体 BRD4 抗体 BRD4 抗体 (ABIN7010051)

BRD4 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

BRD4 抗体  (N-Term) BRD4 抗体  (N-Term) BRD4 抗体 (N-Term) (ABIN6260309)

BRD4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

BRD4 抗体  (AA 1100-1200) BRD4 抗体  (AA 1100-1200) BRD4 抗体 (AA 1100-1200) (ABIN6137653)

BRD4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

BRD4 抗体 by Grade

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BRD4 抗体 by 适用

Find BRD4 抗体 for a variety of species such as anti-Human BRD4, anti-Mouse BRD4, anti-Rat BRD4. The species listed below are among those available. Click on a link to go to the corresponding products.

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BRD4 抗体 by 抗原表位

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BRD4 抗体 by 标记

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Popular BRD4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7010051
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6260309
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6137653
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7127371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (4)
  • (2)
Cat. No. ABIN6242208
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IF, ChIP
Validations
  • (4)
Cat. No. ABIN2780921
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (2)
Cat. No. ABIN7145812
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
  • (1)
Cat. No. ABIN6242209
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5649831
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN214729
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN5649333
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7265946
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7265945
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7265948
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3030205
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our BRD4 抗体

Yamada, Honma, Mochizuki, Goda: "BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver." in: Metabolism: clinical and experimental, Vol. 65, Issue 10, pp. 1478-88, (2017) (PubMed).

Zimmermann, Aguilera, Castellucci, Rossato, Costa, Lunardi, Ostuni, Girolomoni, Natoli, Bazzoni, Tamassia, Cassatella: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." in: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).

Alekseyenko, Walsh, Wang, Grayson, Hsi, Kharchenko, Kuroda, French: "The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains." in: Genes & development, Vol. 29, Issue 14, pp. 1507-23, (2015) (PubMed).

Flajollet, Rachez, Ploton, Schulz, Gallais, Métivier, Pawlak, Leray, Issulahi, Héliot, Staels, Salbert, Lefebvre: "The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors." in: PLoS ONE, Vol. 8, Issue 6, pp. e64880, (2013) (PubMed).

Rahman, Sowa, Ottinger, Smith, Shi, Harper, Howley: "The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3." in: Molecular and cellular biology, Vol. 31, Issue 13, pp. 2641-52, (2011) (PubMed).

Zuber, Shi, Wang, Rappaport, Herrmann, Sison, Magoon, Qi, Blatt, Wunderlich, Taylor, Johns, Chicas, Mulloy, Kogan, Brown, Valent, Bradner, Lowe, Vakoc: "RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia." in: Nature, Vol. 478, Issue 7370, pp. 524-8, (2011) (PubMed).

Mertz, Conery, Bryant, Sandy, Balasubramanian, Mele, Bergeron, Sims: "Targeting MYC dependence in cancer by inhibiting BET bromodomains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 40, pp. 16669-74, (2011) (PubMed).

Powell, Smith, Sowa, Harper, Iftner, Stubenrauch, Howley: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." in: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).

Gagnon, Joubert, Sénéchal, Fradet-Turcotte, Torre, Archambault: "Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4." in: Journal of virology, Vol. 83, Issue 9, pp. 4127-39, (2009) (PubMed).

Sénéchal, Poirier, Coulombe, Laimins, Archambault: "Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4." in: Virology, Vol. 358, Issue 1, pp. 10-7, (2007) (PubMed).

Aliases for BRD4 抗体

bromodomain containing 4 L homeolog (brd4.L) 抗体
bromodomain containing 4 (BRD4) 抗体
bromodomain containing 4 (brd4) 抗体
bromodomain-containing protein 4 (LOC100409351) 抗体
bromodomain containing 4 (Brd4) 抗体
BRD4 抗体
brd4-b 抗体
Brd5 抗体
CAP 抗体
fb18g03 抗体
HUNK1 抗体
HUNKI 抗体
MCAP 抗体
WI-11513 抗体
wu:fb18g03 抗体
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