anti-犬 AIRE 抗体 for Western Blotting

Recommended AIRE Antibody (supplied by: Log in to see )

抗原
Autoimmune Regulator (AIRE) 抗体
  • AIRE1
  • APECED
  • APS1
  • APSI
  • PGA1
  • autoimmune regulator
  • autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • AaeL_AAEL013794
  • CpipJ_CPIJ001208
  • CpipJ_CPIJ001209
  • AIRE
  • Aire
抗原表位
N-Term
37
18
17
15
10
10
6
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 大鼠
147
71
29
10
8
7
5
4
3
2
1
宿主

96
57
18
1
克隆类型
多克隆
标记
This AIRE antibody is un-conjugated
8
6
5
5
5
5
2
2
2
2
2
2
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
147
86
40
35
19
18
13
6
5
5
2
1
1
1
选项
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产品编号 ABIN2779777
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2318885 ABIN2777526 WB Rabbit Middle Region Log in to see Polyclonal 1
3.2318885 ABIN2779775 WB Rabbit N-Term Log in to see Polyclonal 1
3.2318885 ABIN2779776 WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN293603 IHC (p) ELISA WB Goat AA 102-115 Log in to see Polyclonal 0
1 ABIN5553212 EIA IHC (p) WB Goat Internal Region, Isoform 1 Log in to see Polyclonal 0
1 ABIN372242 EIA IHC (p) WB Goat IgG Internal Region Log in to see Polyclonal 0
1 ABIN1731636 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN2615294 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN2560996 IHC ELISA WB Goat IgG Internal Region, Isoform 1 Log in to see Polyclonal 0

General

抗原 Autoimmune Regulator (AIRE) 抗体
抗原表位 N-Term
(37), (18), (17), (15), (10), (10), (6), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 大鼠
(147), (71), (29), (10), (8), (7), (5), (4), (3), (2), (1)
宿主
(96), (57), (18), (1)
克隆类型
多克隆
标记 This AIRE antibody is un-conjugated
(8), (6), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(147), (86), (40), (35), (19), (18), (13), (6), (5), (5), (2), (1), (1), (1)
Pubmed 2个引用可参考
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AIRE抗体详情

AIRE目标详情 使用细节 贮存及处理 References for anti-AIRE antibody (ABIN2779777) 图像
Blocking Peptide Blocking peptide for this product available: ABIN973041
序列 HRTEIAVAVD SAFPLLHALA DHDVVPEDKF QETLHLKEKE GCPQAFHALL
预测反应 Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against AIRE. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE

AIRE目标详情

AIRE抗体详情 使用细节 贮存及处理 References for anti-AIRE antibody (ABIN2779777) 图像 回页首
抗原
别名 AIRE (AIRE Antibody 摘要)
背景 The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Alias Symbols: AIRE1, APECED, APS1, APSI, PGA1
Protein Interaction Partner: TUBB, RAVER1, TUBA1C, TMPRSS13, CCDC87, FAT1, GIGYF2, SRRM2, TUBB4B, EIF4EBP3, UBB, HSP90AB1, HSPA8, HSPA5, HSPA1L, HSPA1A, ATP4A, HIST3H3, HDAC2, HDAC1, DAXX, AIRE, UBAC1, HIST1H3A, HIST2H2BE, HSPA4, SRSF1, SMC1A, XPO1, TOP2A, SSRP1, SNRPD3, SNRPB, SRSF3
Protein Size: 545
分子量 58 kDa
基因ID 326
NCBI登录号 NM_000383, NP_000374
UniProt O43918
途径 Chromatin Binding

使用细节

AIRE抗体详情 AIRE目标详情 贮存及处理 References for anti-AIRE antibody (ABIN2779777) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 545 AA

限制 仅限研究用

贮存及处理

AIRE抗体详情 AIRE目标详情 使用细节 References for anti-AIRE antibody (ABIN2779777) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AIRE antibody (ABIN2779777)

AIRE抗体详情 AIRE目标详情 使用细节 贮存及处理 图像 回页首
背景

Ilmarinen, Kangas, Kytömaa, Eskelin, Saharinen, Seeler, Tanhuanpää, Chan, Slattery, Alakurtti, Palvimo, Ulmanen: "Functional interaction of AIRE with PIAS1 in transcriptional regulation." in: Molecular immunology, Vol. 45, Issue 7, pp. 1847-62, 2008

Akiyoshi, Hatakeyama, Pitkänen, Mouri, Doucas, Kudoh, Tsurugaya, Uchida, Matsushima, Oshikawa, Nakayama, Shimizu, Peterson, Matsumoto: "Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner." in: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33984-91, 2004

图像

AIRE抗体详情 AIRE目标详情 使用细节 贮存及处理 References for anti-AIRE antibody (ABIN2779777) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Autoimmune Regulator (AIRE) (N-Term) antibody (ABIN2779777) WB Suggested Anti-AIRE Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
 image for anti-Autoimmune Regulator (AIRE) (N-Term) antibody (ABIN2779777) anti-Autoimmune Regulator (AIRE) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Autoimmune Regulator (AIRE) (N-Term) antibody (ABIN2779777) anti-Autoimmune Regulator (AIRE) (N-Term) antibody (Image 3)
Western Blotting (WB) image for anti-Autoimmune Regulator (AIRE) (N-Term) antibody (ABIN2779777) AIRE Antibody - N-terminal region (ARP32650_P050) validated by WB using human LCL at ...
Western Blotting (WB) image for anti-Autoimmune Regulator (AIRE) (N-Term) antibody (ABIN2779777) WB Suggested Anti-AIRE
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 ...