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LITAF 抗体

(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008].
LITAF 抗体  (AA 1-161) LITAF 抗体  (AA 1-161) LITAF 抗体 (AA 1-161) (ABIN523000)

LITAF 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

LITAF 抗体 LITAF 抗体 LITAF 抗体 (ABIN7074508)

LITAF 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

LITAF 抗体  (AA 1-161) LITAF 抗体  (AA 1-161) LITAF 抗体 (AA 1-161) (ABIN7158438)

LITAF 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

LITAF 抗体 by Grade

Find LITAF 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 适用

Find LITAF 抗体 for a variety of species such as anti-Human LITAF, anti-Mouse LITAF, anti-Rat LITAF. The species listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 应用范围

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LITAF 抗体 by 抗体来源

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LITAF 抗体 by 抗原表位

Find LITAF 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 克隆形成能力

Find available monoclonal or polyclonal LITAF 抗体. Click on a link to go to the corresponding products.

LITAF 抗体 by 克隆

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LITAF 抗体 by 标记

Find LITAF 抗体 with a specific conjugate such as Biotin, APC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LITAF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN523000
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7074508
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7158438
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7261431
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (3)
Cat. No. ABIN6143254
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN523001
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6262981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1804269
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, IHC (p), ChIP-seq
Validations
  • (2)
Cat. No. ABIN2856656
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243247
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN948817
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN5582604
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN238579
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7307980
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (2)
Cat. No. ABIN371885
Quantity 0.1 mL
Datasheet Datasheet

Latest Publications for our LITAF 抗体

Zhu, Guariglia, Yu, Li, Brancho, Peinado, Lyden, Salzer, Bennett, Chow: "Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1619-37, S1-3, (2013) (PubMed).

Tang, Metzger, Leeman, Amar: "LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 37, pp. 13777-82, (2006) (PubMed).

Saifi, Szigeti, Wiszniewski, Shy, Krajewski, Hausmanowa-Petrusewicz, Kochanski, Reeser, Mancias, Butler, Lupski: "SIMPLE mutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradation." in: Human mutation, Vol. 25, Issue 4, pp. 372-83, (2005) (PubMed).

Moriwaki, Begum, Kobayashi, Matsumoto, Toyoshima, Seya: "Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 23065-76, (2001) (PubMed).

Myokai, Takashiba, Lebo, Amar: "A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4518-23, (1999) (PubMed).

Aliases for LITAF 抗体

lipopolysaccharide induced TNF factor (LITAF) 抗体
lipopolysaccharide-induced TNF factor (Litaf) 抗体
LPS-induced TN factor (Litaf) 抗体
3222402J11Rik 抗体
C85531 抗体
EET-1 抗体
N4WBP3 抗体
PIG7 抗体
Pig7 抗体
SIMPLE 抗体
TBX1 抗体
TNF-alpha 抗体
TP53I7 抗体
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