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Human Monoclonal LILRB2 Primary Antibody for CyTOF, FACS - ABIN4899828
Wenink, Santegoets, Roelofs, Huijbens, Koenen, van Beek, Joosten, Meyer-Wentrup, Mathsson, Ronnelid, Adema, Bonvini, Koenig, van den Berg, van Riel, Radstake: The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease. in Journal of immunology (Baltimore, Md. : 1950) 2009
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Human Monoclonal LILRB2 Primary Antibody for FACS - ABIN4896767
Zimmer, Luce, Gaignier, Nony, Naveau, Biola-Vidamment, Pallardy, Van Overtvelt, Mascarell, Moingeon: Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae. in Journal of immunology (Baltimore, Md. : 1950) 2011
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Human Monoclonal LILRB2 Primary Antibody for FACS - ABIN4896763
Svajger, Obermajer, Jeras: IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses. in Journal of leukocyte biology 2014
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Human Polyclonal LILRB2 Primary Antibody for FACS, WB - ABIN4899824
Banerjee, Lin, Skinner, Schiffhauer, Peacock, Hicks, Redmond, Morrow, Huston, Shayne, Langstein, Miller-Graziano, Strickland, ODonoghue, De: Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression. in Cancer research 2011
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Human Monoclonal LILRB2 Primary Antibody for WB - ABIN395008
Zhang, Yu, Li, Liu, Li, Lin, Gao, Wang, Gao, Sun: ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer. in FEBS letters 2015
Human Monoclonal LILRB2 Primary Antibody for FACS - ABIN4896759
Giles, Shaw, Piper, Wong-Baeza, McHugh, Ridley, Li, Lenart, Antoniou, DiGleria, Kuroki, Maenaka, Bowness, Kollnberger: HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I. in Journal of immunology (Baltimore, Md. : 1950) 2012
Human Polyclonal LILRB2 Primary Antibody for CyTOF, FACS - ABIN4899827
Gleissner, Zastrow, Klingenberg, Kluger, Konstandin, Celik, Haemmerling, Shankar, Giese, Katus, Dengler: IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. in European journal of immunology 2006
Results show that LILRB2 rs383369:AG predisposed to the endometriosis and its progression.
ILT-4 is a receptor for hSEMA4A)on activated CD4 (显示 CD4 抗体)(+) T cells. hSEMA4A is highly expressed in human asthmatic lung tissue.
LILRB2 protein and mRNA expressions are deregulated on monocytes after septic shock
this study shows that sHLA-G causes a functional and quantitative induction of myeloid-derived suppressor cells through engagement of ILT4 and activation of STAT3 (显示 STAT3 抗体)
LILRB2 expression is significantly upregulated in human masticatory mucosa during wound healing
our results indicate that the ILT4-HLA-G (显示 HLAG 抗体) interaction might play an important role in Non-small cell lung cancer progression
in systemic lupus erythematosus (SLE) patients, observed an inhibitory effect of ILT4 on the immunogenic capability of Dendritic cells (DC); ILT4 was shown not to have a crucial role in regulating maturation and function of DC from healthy controls but is partially involved in maturation process and immunogenic capability of DC from SLE patients
Data indicate Ig-like transcript 4 (ILT4) as a cellular receptor for complement split products (CSPs) complement component 4d (C4d).
signaling involving ANGPTL2 (显示 ANGPTL2 抗体) and LILRB2 is important for lung cancer development
Findings suggest that ILT4 drives NSCLC development in part on activation of ERK (显示 EPHB2 抗体) signaling which in turn upregulates VEGF-C (显示 VEGFC 抗体).
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
, leukocyte immunoglobulin-like receptor subfamily B member 2-like
, CD85 antigen-like family member D
, Ig-like transcript 4
, leukocyte immunoglobulin-like receptor subfamily B member 2
, monocyte/macrophage immunoglobulin-like receptor 10