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Human CXCL2 Protein expressed in Wheat germ - ABIN1350823
Nikolakopoulou, Dutta, Chen, Miller, Trapp: Activated microglia enhance neurogenesis via trypsinogen secretion. in Proceedings of the National Academy of Sciences of the United States of America 2013
These results show that AKIP1 (显示 AKIP1 蛋白) is crucial in cervical cancer angiogenesis and growth by elevating the levels of the NF-kappaB (显示 NFKB1 蛋白)-dependent chemokines CXCL1 (显示 CXCL1 蛋白), CXCL2, and CXCL8 (显示 IL8 蛋白).
The studies revealed that, although overall structural and oligomerization features of CXCL3 (显示 CXCL3 蛋白) and CXCL2 are similar, prominent differences were observed in their surface characteristics, thus implicating a functional divergence.
Taken together, the data of the present study demonstrated that TcpC can induce MIP2 production, which may contribute to the characteristic histological change associated with pyelonephritis.
Functional effects data suggested that recombinant human CXCL2 significantly enhanced the migration, invasion ability of SMMC7721 hepatocellular carcinoma cells, and weakened adhesion ability.
Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A (显示 BCL11A 蛋白) and HMIP (显示 MIPEP 蛋白)-2 loci
Results identify the CXCL2/MIF (显示 AMH 蛋白)-CXCR2 (显示 CXCR2 蛋白) axis as an important mediator in MDSC recruitment and as predictors in bladder cancer.
Chronic inflammation contributes to the change of CXCL12 (显示 CXCL12 蛋白) DNA methylation (显示 HELLS 蛋白) in buccal cells and that DNA methylation (显示 HELLS 蛋白) profile of CXCL12 (显示 CXCL12 蛋白) promoter plays important role in development and progression of periodontal disease.
Polymorphisms in the promoter regions of the CXCL1 (显示 CXCL1 蛋白) and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population
In this review, a genetic variant in CXCL12 (显示 CXCL12 蛋白) is described that is associated with type 2 diabetes mellitus and its complications.
We have demonstrated that GRObeta, as an oncogene (显示 RAB1A 蛋白) product, contributed to tumorigenesis and metastasis of HCC (显示 FAM126A 蛋白)
TIARP (显示 STEAP4 蛋白) independently down-regulated CXCL2 and IL-6 (显示 IL6 蛋白) production by fibroblast-like synoviocytes, and the expression of chemokine (显示 CCL1 蛋白) receptors (CXCR1 (显示 CXCR1 蛋白) and CXCR2 (显示 CXCR2 蛋白)) in neutrophils, with resultant reduction of neutrophil migration into arthritic joints.
a paracrine role for Hippo-mediated secretion of CXCL1 (显示 CXCL1 蛋白) and CXCL2 in the production of anti-microbial peptides (beta-defensins), iNOS (显示 NOS2 蛋白), NOX2 (显示 CYBB 蛋白) and pro-inflammatory molecules during mycobacterial infection of the host, is reported.
mip-2 siRNA and the MIP-2 antibody can reduce the inflammatory effects induced by lipopolysaccharide in macrophage cells.
this study demonstrates that in vivo blocking of CXCL1 (显示 CXCL1 蛋白) and CXCL2 can significantly reduce the Mycobacterium tuberculosis-induced bioactive IL-1beta (显示 IL1B 蛋白) production
These data identify suppression of CXCL2 and CXCL5 (显示 CXCL5 蛋白) chemoattractant expression by 11beta-HSD1 (显示 HSD11B1 蛋白) as a novel mechanism with potential for regulation of neutrophil recruitment to the injured myocardium, and cardiac fibroblasts as a key site for intracellular glucocorticoid regeneration during acute inflammation following myocardial injury.
findings show that SRC-3 (显示 NCOA3 蛋白) contributes to host defense against enteric bacteria, at least in part via upregulating CXCL2 expression to recruit neutrophils
p53 (显示 TP53 蛋白)-mediated induction of PAI-1 (显示 SERPINE1 蛋白) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1 (显示 CXCL1 蛋白), CXCL2, and CXCR2 (显示 CXCR2 蛋白).
Social defeat induced an exposure-dependent increase in mRNA levels of E-selectin (显示 SELE 蛋白), CXCL1 (显示 CXCL1 蛋白), and CXCL2 that increased with additional days of social defeat.
reports transmural and perivascular expression patterns of chemokines CCL2 (显示 CCL2 蛋白) and CXCL2 and of chemokine (显示 CCL1 蛋白) receptors CCR2 (显示 CCR2 蛋白), CCR5, and CXCR4 (显示 CXCR4 蛋白) following coronary angioplasty
Results suggested that chemokine (显示 CCL1 蛋白) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
This study examined effects of in vitro exposure to solutions of hay (显示 GTF2H5 蛋白) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
C-X-C motif chemokine 2
, GRO2 oncogene
, MGSA beta
, growth-regulated protein beta
, macrophage inflammatory protein 2-alpha
, melanoma growth stimulatory activity beta
, GRO3 oncogene
, GRO3, growth related gene 3
, growth-regulated protein homolog gamma
, macrophage inflammatory protein 2
, small inducible cytokine subfamily, member 2
, cytokine-induced neutrophil chemoattractant 3
, chemokine ligand 2