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HAP1 抗体

(Huntingtin Associated Protein 1 (HAP1))
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
HAP1 抗体 HAP1 抗体 HAP1 抗体 (ABIN534035)

HAP1 适用: 大鼠 WB, IHC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 1B6 unconjugated

HAP1 抗体  (Internal Region) HAP1 抗体  (Internal Region) HAP1 抗体 (Internal Region) (ABIN334416)

Verified HAP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

HAP1 抗体  (AA 132-328) HAP1 抗体  (AA 132-328) HAP1 抗体 (AA 132-328) (ABIN5013715)

HAP1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

HAP1 抗体 by Grade

Find HAP1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

HAP1 抗体 by 适用

Find HAP1 抗体 for a variety of species such as anti-Human HAP1, anti-Rat HAP1, anti-Mouse HAP1. The species listed below are among those available. Click on a link to go to the corresponding products.

HAP1 抗体 by 应用范围

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HAP1 抗体 by 抗体来源

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HAP1 抗体 by 抗原表位

Find HAP1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HAP1 抗体 by 克隆形成能力

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HAP1 抗体 by 克隆

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HAP1 抗体 by 标记

Find HAP1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, IHC (p), IHC (fro)
Validations
  • (2)
  • (2)
Cat. No. ABIN534035
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN334416
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5013715
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7155933
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN522442
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN948757
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN190785
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5013714
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1868320
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN499942
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155936
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7155935
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155934
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF
Validations
Cat. No. ABIN6990748
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7267795
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our HAP1 抗体

Xiang, Yang, Xin, Gaertig, Reeves, Li, Li: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).

Corradini, Burgers, Plank, Heck, Scholten: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).

Corradini, Vallur, Raaijmakers, Feil, Feil, Heck, Scholten: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).

Ma, Savas, Yu, Culver, Chao, Tanese: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." in: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).

Borrell-Pagès, Zala, Humbert, Saudou: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." in: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).

Rong, McGuire, Fang, Sheng, Shin, Li, Li: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).

Takeshita, Fujinaga, Zhao, Yanai, Shinoda: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." in: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).

Gauthier, Charrin, Borrell-Pagès, Dompierre, Rangone, Cordelières, De Mey, MacDonald, Lessmann, Humbert, Saudou: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." in: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).

Gutekunst, Torre, Sheng, Yi, Coleman, Riedel, Bujo: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Aliases for HAP1 抗体

huntingtin associated protein 1 (HAP1) 抗体
huntingtin-associated protein 1 (Hap1) 抗体
HAP-1 抗体
HAP1-A 抗体
HAP1-B 抗体
HAP2 抗体
hHLP1 抗体
HIP5 抗体
HLP 抗体
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