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Human Polyclonal FOXO4 Primary Antibody for WB - ABIN965517
Burnett, Barrow, Cohen, Snyder, Sabatini: RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. in Proceedings of the National Academy of Sciences of the United States of America 1998
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Human FOXO4 Primary Antibody for IHC, WB - ABIN965516
Di, Hao, Gao, Wang, Wang, Qiu, Wen, Zhou, Wu, Lu, Liao, Mei, Zheng, Che: Monoclonal antibody-based antigen capture enzyme-linked immunosorbent assay reveals high sensitivity of the nucleocapsid protein in acute-phase sera of severe acute respiratory syndrome patients. in Clinical and diagnostic laboratory immunology 2005
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Human Polyclonal FOXO4 Primary Antibody for IF, IHC - ABIN362126
Kops, de Ruiter, De Vries-Smits, Powell, Bos, Burgering: Direct control of the Forkhead transcription factor AFX by protein kinase B. in Nature 1999
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Human Polyclonal FOXO4 Primary Antibody for EIA, ELISA - ABIN252952
Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. in Cell 2007
FOXO1 (显示 FOXO1 抗体), 3, and 4 as well as their upstream regulator, AKT/p-AKT (显示 AKT1 抗体), was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult
The results of this genomic analysis suggest that low FOXO4 expression is a significant risk factor for epileptic seizures in patients with LGGs and is associated with the seizure outcome.
NF-kappaB (显示 NFKB1 抗体)/snail (显示 SNAI1 抗体)/YY1 (显示 YY1 抗体)/RKIP (显示 PEBP1 抗体) circuitry regulated by FOXO4 were likely involved in miR (显示 MLXIP 抗体)-150-induced EMT (显示 ITK 抗体) event.
Negative expression of FoxO3 (显示 FOXO3 抗体)/FoxO4 and lymph node metastasis were the risk factors for the poor prognosis of bladder cancer.
Knockdown of FOXO4 but not FOXO1 (显示 FOXO1 抗体) expression decreased proteasome activity. Following neural differentiation, the HD-iPSC-derived neural progenitor cells (NPCs) demonstrated lower levels of proteasome activity and FOXO (显示 FOXO3 抗体) expressions than their WT counterparts. More importantly, overexpression of FOXO4 but not FOXO1 (显示 FOXO1 抗体) in HD NPCs dramatically enhanced proteasome activity.
Results show that a small subset of lymphoma cells surviving treatment with doxorubicin or phenylbutyrate showed stem cell-like properties and resistance to chemotherapeuty. The overexpression of FOXO4 was found in these surviving cells, and DLBCL patients with FOXO4-positive tumor cells had poor prognosis.
FOXO4 and FOXD3 (显示 FOXD3 抗体) were shown independently predictive of overall survival in gastric cancer
FoxO1 (显示 FOXO1 抗体) and FoxO4 antagonize Tat (显示 TAT 抗体)-mediated transactivation of HIV-1 promoter through the repression of Tat (显示 TAT 抗体) protein expression.
FOXO4 has an inhibitory effect in clearcell renal carcinoma (显示 TSC2 抗体) cells, at least in part through inducing apoptosis via upregulation of Bim (显示 BCL2L11 抗体) in the mitochondria-dependent pathway.
knockdown of Ku70 (显示 XRCC6 抗体) inhibited cell proliferation accompanying an increase in p27(kip1 (显示 CDKN1B 抗体)) levels through interacting with FOXO4
miR (显示 MLXIP 抗体)-664 functions as an oncogene (显示 RAB1A 抗体) miRNA and has an important role in promoting human osteosarcoma cell proliferation by suppressing FOXO4 expression.
Foxo1 (显示 FOXO1 抗体), Foxo3a (显示 FOXO3 抗体), and Foxo4 in chondrocytes regulate endochondral bone formation.
The effect of Sirt1 (显示 SIRT1 抗体) stimulators on osteoclastogenesis was abrogated in cells lacking FoxO1 (显示 FOXO1 抗体), FoxO3 (显示 FOXO3 抗体), and FoxO4.
FoxO4 is collectively required to maintain MODYrelated gene networks, which in turn are required to enable a gene expression program that permits proper substrate selection (glucose versus fatty acids) for mitochondrial oxidative phosphorylation.
FoxO4 transcription factor is present during both oocyte and embryo in vivo maturation and FoxOs may regulate in vitro embryo development under stress conditions.
FoxO4 activates Arg1 (显示 ARG1 抗体) transcription in endothelial cells in response to MI, leading to downregulation of nitric oxide and upregulation of neutrophil infiltration to the infarct area.
Foxo1, Foxo3, and Foxo4 transcriptional network regulates autophagy and the ubiquitin-proteasome system during muscle atrophy.
Liver-specific ablation of FoxO1 (显示 FOXO1 抗体),FoxO3 (显示 FOXO3 抗体) and FoxO4 prevents the induction of glucose-6-phosphatase (显示 G6PC 抗体) and the repression of glucokinase (显示 GCK 抗体) during fasting, thus increasing lipogenesis.
FOXO1 (显示 FOXO1 抗体), FOXO3a (显示 FOXO3 抗体) and FOXO4, are indispensable for SIRT1 (显示 SIRT1 抗体)-dependent cell survival against oxidative stress.
FoxO1 (显示 FOXO1 抗体)/3/4 transcription factors play important roles in hepatic glucose homeostasis.
Mice lacking Foxo1 (显示 FOXO1 抗体), -3, and -4 in bipotential progenitors of osteoblast and adipocytes exhibit increased osteoblast number and high bone mass.
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
similar to Putative fork head domain transcription factor AFX1 (Forkhead box protein O4)
, forkhead box O4
, forkhead box protein O4-like
, fork head domain transcription factor AFX1
, forkhead box protein O4
, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7
, forkhead protein
, myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog
, forkhead box O1A