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COPS5 抗体

(COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].
COPS5 抗体 COPS5 抗体 COPS5 抗体 (ABIN7266497)

COPS5 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated

COPS5 抗体  (AA 1-334) COPS5 抗体  (AA 1-334) COPS5 抗体 (AA 1-334) (ABIN3022512)

COPS5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

COPS5 抗体 COPS5 抗体 COPS5 抗体 (ABIN7259711)

COPS5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

COPS5 抗体 by 适用

Find COPS5 抗体 for a variety of species such as anti-Human COPS5, anti-Mouse COPS5, anti-Rat COPS5. The species listed below are among those available. Click on a link to go to the corresponding products.

COPS5 抗体 by 应用范围

Find COPS5 抗体 validated for a specific application such as WB, IHC, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

COPS5 抗体 by 抗体来源

Find COPS5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

COPS5 抗体 by 抗原表位

Find COPS5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

COPS5 抗体 by 克隆形成能力

Find available monoclonal or polyclonal COPS5 抗体. Click on a link to go to the corresponding products.

COPS5 抗体 by 克隆

Find COPS5 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

COPS5 抗体 by 标记

Find COPS5 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular COPS5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, ChIP
Validations
  • (7)
Cat. No. ABIN7266497
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN3022512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7259711
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (3)
Cat. No. ABIN7256932
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6260970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3042754
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7235241
Quantity 200 μL
Datasheet Datasheet
Reactivity Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6735871
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IP
Validations
  • (2)
Cat. No. ABIN337275
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN685912
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6242680
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p), IP
Validations
  • (1)
Cat. No. ABIN214239
Quantity 50 μg
Datasheet Datasheet
Reactivity Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6742215
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN1533317
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7297862
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our COPS5 抗体

Karpiyevich, Adjalley, Mol, Ascher, Mason, van der Heden van Noort, Laman, Ovaa, Lee, Artavanis-Tsakonas: "Nedd8 hydrolysis by UCH proteases in Plasmodium parasites." in: PLoS pathogens, Vol. 15, Issue 10, pp. e1008086, (2019) (PubMed).

Wang, Wang, Carrera, Xu, Lakshmana: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).

Wang, Dey, Carrera, Minond, Bianchi, Xu, Lakshmana: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." in: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).

Merk, Zierow, Leng, Das, Du, Schulte, Fan, Lue, Chen, Xiong, Chagnon, Bernhagen, Lolis, Mor, Lesur, Bucala: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).

Mitsuhashi, Yonemoto, Sone, Kosuge, Kosaki, Takahashi: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).

McCall, Miliani de Marval, Chastain, Jackson, He, Kotake, Cook, Xiong: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).

da Silva Correia, Miranda, Leonard, Ulevitch: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).

Burger-Kentischer, Finkelmeier, Thiele, Schmucker, Geiger, Tovar, Bernhagen: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." in: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).

Kamura, Hara, Matsumoto, Ishida, Okumura, Hatakeyama, Yoshida, Nakayama, Nakayama: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." in: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).

Yun, Tomida, Andoh, Tsuruo: "Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31296-303, (2004) (PubMed).

Aliases for COPS5 抗体

COP9 signalosome subunit 5 (CSN5) 抗体
COP9 signalosome subunit 5 (COPS5) 抗体
COP9 signalosome subunit 5 (cops5) 抗体
COP9 signalosome complex subunit 5 (CpipJ_CPIJ012314) 抗体
COP9 signalosome complex subunit 5 (Bm1_46585) 抗体
COP9 signalosome complex subunit 5 (VDBG_06932) 抗体
COP9 signalosome complex subunit 5 (LOAG_01443) 抗体
COP9 signalosome complex subunit 5 (csn5) 抗体
COP9 signalosome subunit 5 (Cops5) 抗体
COP9 signalosome subunit 5 S homeolog (cops5.S) 抗体
COP9 signalosome complex subunit 5 (csn-5) 抗体
AI303502 抗体
BcDNA.LD14392 抗体
BcDNA:LD14392 抗体
CG14884 抗体
CH5 抗体
COPS5 抗体
CSN-5 抗体
Csn5 抗体
csn5 抗体
CSN5 抗体
DCH5 抗体
Dch5 抗体
dch5 抗体
Dmel\\CG14884 抗体
JAB1 抗体
Jab1 抗体
JAB1/CSN5 抗体
jab1/csn5 抗体
JadBp 抗体
l(3)89Cf 抗体
l(3)L4032 抗体
l(3)M203 抗体
MGC76063 抗体
MOV-34 抗体
Mov34 抗体
quo 抗体
Sgn5 抗体
SGN5 抗体
zgc:73130 抗体
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