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Transforming Growth Factor, beta 2 蛋白

(Transforming Growth Factor, beta 2 (TGFB2))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
TGFB2 Protein (His tag) TGFB2 Protein (His tag) TGFB2 Protein (His tag) (ABIN1112028)

TGFB2 宿主: 人 宿主: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS-PAGE gel WB, Imm, ELISA, STD

TGFB2 Protein (AA 303-414) TGFB2 Protein (AA 303-414) TGFB2 Protein (AA 303-414) (ABIN7275710)

TGFB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

TGFB2 Protein (AA 303-414) (AVI tag,Biotin) TGFB2 Protein (AA 303-414) (AVI tag,Biotin) TGFB2 Protein (AA 303-414) (AVI tag,Biotin) (ABIN7275711)

TGFB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

Transforming Growth Factor, beta 2 蛋白 by Grade

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Transforming Growth Factor, beta 2 蛋白 by Origin

Find Transforming Growth Factor, beta 2 蛋白 for a variety of species such as anti-Human Transforming Growth Factor, beta 2, anti-Mouse Transforming Growth Factor, beta 2, anti-Chicken Transforming Growth Factor, beta 2. The species listed below are among those available. Click on a link to go to the corresponding products.

Transforming Growth Factor, beta 2 蛋白 by Source

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Transforming Growth Factor, beta 2 蛋白 by 蛋白类型

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Transforming Growth Factor, beta 2 蛋白 by 应用范围

Find Transforming Growth Factor, beta 2 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Transforming Growth Factor, beta 2 蛋白 by 生物活性

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Popular Transforming Growth Factor, beta 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
  • (4)
  • (2)
Cat. No. ABIN1112028
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275711
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1785602
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320669
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074159
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074158
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133505
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133504
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505540
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505428
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505179
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
Cat. No. ABIN7507930
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN6964328
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
Cat. No. ABIN4371497
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Transforming Growth Factor, beta 2 蛋白

Zou, Sun: "An improved recombinant mammalian cell expression system for human transforming growth factor-beta2 and -beta3 preparations." in: Protein expression and purification, Vol. 50, Issue 1, pp. 9-17, (2006) (PubMed).

Massagué: "The transforming growth factor-beta family." in: Annual review of cell biology, Vol. 6, pp. 597-641, (1991) (PubMed).

Miller, Pelton, Derynck, Moses: "Transforming growth factor-beta. A family of growth regulatory peptides." in: Annals of the New York Academy of Sciences, Vol. 593, pp. 208-17, (1990) (PubMed).

Webb, Madisen, Rose, Purchio: "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 7, pp. 493-7, (1989) (PubMed).

ten Dijke, Hansen, Iwata, Pieler, Foulkes: "Identification of another member of the transforming growth factor type beta gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 13, pp. 4715-9, (1988) (PubMed).

de Martin, Haendler, Hofer-Warbinek, Gaugitsch, Wrann, Schlüsener, Seifert, Bodmer, Fontana, Hofer: "Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family." in: The EMBO journal, Vol. 6, Issue 12, pp. 3673-7, (1988) (PubMed).

Madisen, Webb, Rose, Marquardt, Ikeda, Twardzik, Seyedin, Purchio: "Transforming growth factor-beta 2: cDNA cloning and sequence analysis." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 1, pp. 1-8, (1988) (PubMed).

Aliases for Transforming Growth Factor, beta 2 蛋白

transforming growth factor beta 2 (TGFB2) 蛋白
transforming growth factor beta 2 L homeolog (tgfb2.L) 蛋白
transforming growth factor, beta 2 (Tgfb2) 蛋白
transforming growth factor, beta receptor 2 (Tgfbr2) 蛋白
transforming growth factor, beta 2 (tgfb2) 蛋白
transforming growth factor beta 2 (Tgfb2) 蛋白
BB105277 蛋白
LDS4 蛋白
MGF 蛋白
TGF-B2 蛋白
TGF-beta2 蛋白
tgf-beta2 蛋白
Tgf-beta2 蛋白
TGF-beta 2 蛋白
Tgfb-2 蛋白
TGFB2 蛋白
tgfb2-A 蛋白
TGFbeta2 蛋白
Tgfbr2T 蛋白
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