Use your antibodies-online credentials, if available.
抗Mouse (Murine) Occludin 抗体:
抗Rat (Rattus) Occludin 抗体:
抗Human Occludin 抗体:
Human Polyclonal Occludin Primary Antibody for IF (p), IHC (p) - ABIN687337
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
Show all 5 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, WB - ABIN968361
Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. in The Journal of cell biology 1996
Show all 3 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, WB - ABIN968360
Bolton, Anthony, Perry: Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. in Neuroscience 1998
Show all 3 Pubmed References
Human Polyclonal Occludin Primary Antibody for ICC, IF - ABIN4341293
Liu, Schrott-Fischer, Glueckert, Benav, Rask-Andersen: The Human "Cochlear Battery" - Claudin-11 Barrier and Ion Transport Proteins in the Lateral Wall of the Cochlea. in Frontiers in molecular neuroscience 1970
Show all 2 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, IHC (p) - ABIN337048
Krueger, Härtig, Reichenbach, Bechmann, Michalski: Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions. in PLoS ONE 2013
Human Polyclonal Occludin Primary Antibody for IHC (fro), IF - ABIN2192203
Van Itallie, Anderson: Occludin confers adhesiveness when expressed in fibroblasts. in Journal of cell science 1997
Human Polyclonal Occludin Primary Antibody for ELISA, ICC - ABIN4341292
Liu, Xu, Ji, Liu, Mo, Tollerud, Gu, Zhang: Sublethal effects of zinc oxide nanoparticles on male reproductive cells. in Toxicology in vitro : an international journal published in association with BIBRA 2016
Cow (Bovine) Polyclonal Occludin Primary Antibody for WB - ABIN2775620
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. in The Journal of cell biology 2008
Show all 2 Pubmed References
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin and zonula occludens 1 (显示 TJP1 抗体).
The zinc sensing receptor, ZnR/GPR39 (显示 GPR39 抗体), triggers intracellular Ca(2 (显示 CA2 抗体)+) signalling in colonocytes thereby inducing occludin expression. Moreover, ZnR/GPR39 (显示 GPR39 抗体) is essential for epithelial barrier recovery in the dextran sodium sulfate (DSS (显示 PMP22 抗体)) ulcerative colitis model.
Occludin expression by epidermal gammadelta T cells upon activation in response to epidermal stress allows them to move, which could be important for augmentation of immune responses via collaboration with other cells.
Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (显示 CLDN3 抗体) transcription.
miR (显示 MLXIP 抗体)-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR (显示 UTS2R 抗体), which impaired intestinal barrier function in diabetes mellitus mice.
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Tricellulin (显示 MARVELD2 抗体) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (显示 EGLN3 抗体) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (显示 EGLN3 抗体) in stabilizing occludin
ZO-1 (显示 TJP1 抗体) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
ADMA has potent adverse effects on cell proliferation, intracellular ROS (显示 ROS1 抗体) generation, cell permeability, levels of ICAM-1 (显示 ICAM1 抗体), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (显示 TJP1 抗体) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (显示 VEGFA 抗体)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
decreased interaction between ZO-1 (显示 TJP1 抗体) and occludin might contribute to the epiphora occurred in the transplanted submandibular glands
integration of claudin-2 (显示 CLDN2 抗体), occludin and ZO-1 (显示 TJP1 抗体) is necessary for maintaining the function of the proximal tubular epithelium.
Molecular studies of the OCLN gene (NM_001205254) identified six distinct candidate mutations in polymicrogyria.
Glutamine (显示 GFPT1 抗体) increased claudin-1 (显示 CLDN7 抗体) expression in the colonic mucosa of patients with irritable bowel syndrome. In contrast, occludin expression was not significantly modified by glutamine (显示 GFPT1 抗体).
Viral infectivity was significantly reduced by miR (显示 MLXIP 抗体)-200c but enhanced by miR (显示 MLXIP 抗体)-122.
The mechanism of transition from nondifferentiated to differentiated states in HepaRG cells was studed by proteomics. Two key factors (MMP-14 (显示 MMP14 抗体) and OCLN) were validated by qRT-PCR and Western blot.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (显示 MLXIP 抗体)-34c bound together to regulate the expressions of MAZ (显示 MAZ 抗体), ZO-1 (显示 TJP1 抗体) and occludin.
Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight-junction protein
, thiopurine methyltransferase
, tight junction protein occludin