anti-人 Tumor Necrosis Factor 抗体 for Immunohistochemistry

Recommended Tumor Necrosis Factor Antibody (supplied by: Log in to see )

抗原
Tumor Necrosis Factor (TNF) 抗体
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • lipopolysaccharide induced TNF factor
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LITAF
  • LOC103694380
  • tnfa
适用
人, 小鼠, 大鼠
1380
528
457
229
223
203
202
59
56
44
32
18
15
9
7
6
6
5
4
4
4
4
3
2
2
1
1
1
1
宿主

1071
543
138
50
11
10
8
7
5
2
1
克隆类型
多克隆
标记
This Tumor Necrosis Factor antibody is un-conjugated
185
95
71
55
49
26
23
22
21
20
19
19
19
19
19
19
18
17
11
11
11
11
11
11
11
11
11
11
11
11
11
11
11
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
应用范围
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
828
804
756
466
403
269
206
169
134
120
100
67
48
42
26
26
25
17
15
13
9
9
9
7
6
6
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
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产品编号 ABIN6269443
$ 450.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.854502 ABIN153474 IHC (p) IHC ELISA WB Rabbit Log in to see Polyclonal 9
8.854502 ABIN5596796 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
8.854502 ABIN2707185 IHC WB Rabbit Center Log in to see Polyclonal 0
8.854502 ABIN3188055 IHC WB Rabbit IgG Log in to see Polyclonal 0
8.854502 ABIN1533583 IF IHC ELISA Rabbit IgG AA 141-190 Log in to see Polyclonal 0
8.854502 ABIN1875123 IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
8.854502 ABIN3188057 IHC WB Mouse IgG1 Log in to see Q36 0
8.854502 ABIN3188056 IHC WB Mouse IgG1 Log in to see Q34 0
8.854502 ABIN305730 ELISA FACS IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 52B83 0
8.854502 ABIN959235 IHC IHC (p) Mouse IgG1 Log in to see 2C8 0
8.854502 ABIN790510 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-234 Log in to see M 1 C4 0
8.854502 ABIN573983 ELISA ELISpot IHC IHC (p) Mouse IgG1, kappa Log in to see MAb1 0
8.854502 ABIN1172395 ICC IHC WB Rabbit IgG AA 77-233 Log in to see Polyclonal 0
8.854502 ABIN2852671 IHC WB Mouse Log in to see 0
8.854502 ABIN1846088 IF/ICC IHC Rabbit Log in to see Polyclonal 0
8.854502 ABIN1104720 IHC IHC (p) Neut WB Rabbit Log in to see Polyclonal 0
8.854502 ABIN5964851 IHC WB Rabbit IgG Log in to see Polyclonal 0
8.854502 ABIN3020863 IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
8.854502 ABIN5589758 ELISA IHC WB Mouse IgG1 Log in to see 4E1 0
8.854502 ABIN2470862 IHC ELISA Mouse IgG1 kappa Log in to see MAb1 0

General

抗原 Tumor Necrosis Factor (TNF) 抗体
适用 人, 小鼠, 大鼠
(1380), (528), (457), (229), (223), (203), (202), (59), (56), (44), (32), (18), (15), (9), (7), (6), (6), (5), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1)
宿主
(1071), (543), (138), (50), (11), (10), (8), (7), (5), (2), (1)
克隆类型
多克隆
标记 This Tumor Necrosis Factor antibody is un-conjugated
(185), (95), (71), (55), (49), (26), (23), (22), (21), (20), (19), (19), (19), (19), (19), (19), (18), (17), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
应用范围 ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(828), (804), (756), (466), (403), (269), (206), (169), (134), (120), (100), (67), (48), (42), (26), (26), (25), (17), (15), (13), (9), (9), (9), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 10个引用可参考
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Tumor Necrosis Factor抗体详情

Tumor Necrosis Factor目标详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN6269443) 图像
特异性 TNFA Antibody detects endogenous levels of total TNFA
交叉反应 人, 小鼠, 大鼠
纯化方法 The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
免疫原 A synthesized peptide derived from human TNFA
亚型 IgG
Plasmids, Primers & others

Tumor Necrosis Factor目标详情

Tumor Necrosis Factor抗体详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN6269443) 图像 回页首
抗原
别名 TNFA (TNF Antibody 摘要)
背景

Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).

Gene: TNF

分子量 17/30-35kDa
基因ID 7124
UniProt P01375
途径 NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

使用细节

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN6269443) 图像 回页首
应用备注 WB 1:500 IHC 1:50-1:200 IF/ICC 1:100-1:500
限制 仅限研究用

贮存及处理

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 References for anti-Tumor Necrosis Factor antibody (ABIN6269443) 图像 回页首
状态 Liquid
浓度 1 mg/mL
缓冲液 PBS,  pH 7.4,50 % glycerol.

References for anti-Tumor Necrosis Factor antibody (ABIN6269443)

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Sun, Xu, Yi, Chen, Wu, Cao, Zhou, Jiang, Zhang: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, 2018

Feng, Cui, Liu, Wu, Hu, Zhang, Ma, Wang: "Protective Role of Apocynin via Suppression of Neuronal Autophagy and TLR4/NF-κB Signaling Pathway in a Rat Model of Traumatic Brain Injury." in: Neurochemical research, Vol. 42, Issue 11, pp. 3296-3309, 2018

Hu, Cheng, Huang, Cai, Lian, Wang, Gao: "Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 42, pp. 245-257, 2018

Sheng, Wang, Guo, Xu, Jiang, Zheng, Xu, Zhang, Che, Liang, Zhu, Li: "Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 3, pp. 986-998, 2018

Zhu, Xu, Lv, He, Ye, Wang, Hu: "miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3β and NF-κB Pathways." in: Inflammation, Vol. 41, Issue 4, pp. 1524-1535, 2018

Guo, Sheng, Dan, Xu, Zhang, Ji, Wang, Xu, Che, Li, Liang, Li: "Involvement of P2Y12 receptor of stellate ganglion in diabetic cardiovascular autonomic neuropathy." in: Purinergic signalling, 2018

Yuan, Ouyang, Yang, Li, Gong, Zou, Jia, Zhao, Wu, Yi, Liu, Shi, Li, Gao, Li, Xu, Liu, Zhang, Liang: "Osthole alleviated diabetic neuropathic pain mediated by the P2X4 receptor in dorsal root ganglia." in: Brain research bulletin, Vol. 142, pp. 289-296, 2018

Feng, Gao, Cui, Li, Li, Cui, Cui: "Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway." in: Cellular and molecular neurobiology, Vol. 37, Issue 1, pp. 155-168, 2017

Zhang, Zou, Zhang, Fu, Xu, Wang, Xia, Huang, Gan, Zhu, Xu: "A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation." in: Experimental neurology, Vol. 297, pp. 1-13, 2017

Feng, Cui, Gao, Li, Li, Jiang, Tian, Wang, Cui, Cui: "Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 921-30, 2016

图像

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN6269443) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Western blot analysis of extracts from COLO cells,using TNFA Antibody.The lane on the...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, usin...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) ABIN6269444 staining A-431 cells by IF/ICC. The sample were fixed with PFA and permea...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Western blot analysis of extracts of various celllines,using TNFA antibody.