anti-人 Tumor Necrosis Factor 抗体 for Immunohistochemistry

Recommended Tumor Necrosis Factor Antibody (supplied by: Log in to see )

抗原
Tumor Necrosis Factor (TNF) 抗体
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LOC103694380
  • tnfa
适用

1380
530
459
229
223
203
202
59
56
44
32
18
15
9
7
6
6
5
4
4
4
4
3
2
2
1
1
1
1
宿主

1071
543
138
52
11
10
8
7
5
2
1
克隆类型
多克隆
标记
This Tumor Necrosis Factor antibody is un-conjugated
185
95
71
55
49
26
23
22
21
20
19
19
19
19
19
19
18
17
11
11
11
11
11
11
11
11
11
11
11
11
11
11
11
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
应用范围
Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
830
806
756
468
405
269
206
170
133
120
100
67
48
42
26
26
25
17
15
13
9
9
9
7
6
6
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
选项
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产品编号 ABIN5596796
$ 583.50
Plus shipping costs $45.00 and $23.00 dry ice
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
29.492777 ABIN6269443 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 10
27.748459 ABIN3188055 IHC WB Rabbit IgG Log in to see Polyclonal 0
24.748459 ABIN3188056 IHC WB Mouse IgG1 Log in to see Q34 0
24.748459 ABIN3020863 IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
21.748459 ABIN3188057 IHC WB Mouse IgG1 Log in to see Q36 0
18.992777 ABIN1875123 IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
18.755682 ABIN6149290 IHC WB Rabbit Log in to see Polyclonal 0
15.755682 ABIN3187296 ELISA IF IHC Rabbit IgG Internal Region Log in to see Polyclonal 0
13 ABIN6171930 FACS IF IHC APC Mouse IgM, kappa Log in to see TNFA-1172 0
13 ABIN6171937 FACS IF IHC PerCP Mouse IgM, kappa Log in to see TNFA-1172 0
13 ABIN6171938 FACS IF IHC PE Mouse IgM, kappa Log in to see TNFA-1172 0
13 ABIN6171941 FACS IF IHC Mouse IgM, kappa Log in to see TNFA-1172 0
12.992777 ABIN790510 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-234 Log in to see M 1 C4 0
12.992777 ABIN1172395 ICC IHC WB Rabbit IgG AA 77-233 Log in to see Polyclonal 0
12.755682 ABIN5668145 BR ELISA IF IHC Human IgG1, kappa Log in to see D2E7 (Adalimumab) 0
12.755682 ABIN5668146 BR ELISA IF IHC Rabbit IgG, kappa Log in to see Chimeric 0
12.755682 ABIN5620992 IHC WB Rabbit Center Log in to see Polyclonal 0
12.755682 ABIN284915 Inhibition IHC ELISA Mouse IgG1 Log in to see M32253 0
12.755682 ABIN284821 Inhibition IHC ELISA Mouse IgG1 Log in to see 1D9 0
12.755682 ABIN284916 IHC ELISA Mouse IgG1 Log in to see M32255 0

General

抗原 Tumor Necrosis Factor (TNF) 抗体
适用
(1380), (530), (459), (229), (223), (203), (202), (59), (56), (44), (32), (18), (15), (9), (7), (6), (6), (5), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1)
宿主
(1071), (543), (138), (52), (11), (10), (8), (7), (5), (2), (1)
克隆类型
多克隆
标记 This Tumor Necrosis Factor antibody is un-conjugated
(185), (95), (71), (55), (49), (26), (23), (22), (21), (20), (19), (19), (19), (19), (19), (19), (18), (17), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
应用范围 Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(830), (806), (756), (468), (405), (269), (206), (170), (133), (120), (100), (67), (48), (42), (26), (26), (25), (17), (15), (13), (9), (9), (9), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 找到1个引用
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Tumor Necrosis Factor抗体详情

Tumor Necrosis Factor目标详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN5596796) 图像
特异性 This antibody is primarily directed against mature 17,000 MW human TNFalpha and is useful in determining its presence in various assays. In general, this antibody also detects primate TNFalpha in the same formats using similar dilutions. The antibody does not recognize human TNGß (lymphotoxin). This IgG fraction antibody will recognize the cell-bound precursor of TNFalpha as a 26,000 protein in immunoblots, particularly in denatured samples. This antibody is also useful for neutralization of human and primate TNFalpha activity in bioassays. It does not neutralize the biological activity of lymphotoxin. For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested. A control of similarly diluted normal rabbit IgG is recommended.
产品特性 Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-alpha) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
过滤 Sterile filtered
免疫原 The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha produced in E.coli.
Immunogen Type: RecombinantProtein
亚型 IgG
Plasmids, Primers & others

Tumor Necrosis Factor目标详情

Tumor Necrosis Factor抗体详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN5596796) 图像 回页首
抗原
别名 TNF alpha (TNF Antibody 摘要)
背景 Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-α) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
Synonyms: APC1 antibody, Cachectin antibody, DIF antibody, Differentiation inducing factor antibody, Macrophage cytotoxic factor antibody, MCF antibody, Necrosin antibody
基因ID 7124
UniProt P01375
途径 NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

使用细节

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN5596796) 图像 回页首
应用备注 This IgG fraction antibody of anti-Human TNFα has been tested for use in neutralizations, ELISA, immunohistochemistry and immunoblotting. It recognizes the 17,000 MW TNFα. Reactivity in other immunoassays is unknown.
说明

Gene Name: TNFA

限制 仅限研究用

贮存及处理

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 References for anti-Tumor Necrosis Factor antibody (ABIN5596796) 图像 回页首
状态 Liquid
浓度 1.0 mg/mL
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
储存液 Without preservative
储存条件 4 °C/-20 °C
储存方法 Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
有效期 12 months

References for anti-Tumor Necrosis Factor antibody (ABIN5596796)

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Kant, Swat, Zhang, Zhang, Neel, Flavell, Davis: "TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway." in: Genes & development, Vol. 25, Issue 19, pp. 2069-78, 2011

图像

Tumor Necrosis Factor抗体详情 Tumor Necrosis Factor目标详情 使用细节 贮存及处理 References for anti-Tumor Necrosis Factor antibody (ABIN5596796) 回页首
厂商提供的图像
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) anti-Tumor Necrosis Factor (TNF) antibody
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) anti-Tumor Necrosis Factor (TNF) antibody (Image 2)
Immunofluorescence (IF) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Fluorescent immunohistochemistry showing staining of human colon by anti-TNF alpha (...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western blot of Anti-Human TNF-a (RABBIT) Antibody. Lane 1: 250ng human recombinant T...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western Blot of Rabbit anti-TNF Alpha antibody. Marker: Opal Pre-stained ladder . Lan...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western blot using Anti-Human TNF-a (RABBIT) Antibody. Membrane blocked in 1% BSA-TB...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Immunohistochemistry using polyclonal TNFa antibody showing staining of formalin/PFA...