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LIM Domain Kinase 1 抗体

(LIM Domain Kinase 1 (LIMK1))
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Feb 2011].
LIM Domain Kinase 1 抗体  (pThr508) LIM Domain Kinase 1 抗体  (pThr508) LIM Domain Kinase 1 抗体 (pThr508) (ABIN6255701)

LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

LIM Domain Kinase 1 抗体 LIM Domain Kinase 1 抗体 LIM Domain Kinase 1 抗体 (ABIN1499146)

LIMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H6 unconjugated

LIM Domain Kinase 1 抗体 LIM Domain Kinase 1 抗体 LIM Domain Kinase 1 抗体 (ABIN1499147)

LIMK1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 6B4 unconjugated

LIM Domain Kinase 1 抗体 by 适用

Find LIM Domain Kinase 1 抗体 for a variety of species such as anti-Human LIM Domain Kinase 1, anti-Mouse LIM Domain Kinase 1, anti-Rat LIM Domain Kinase 1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find LIM Domain Kinase 1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Popular LIM Domain Kinase 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (43)
Cat. No. ABIN6255701
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (6)
Cat. No. ABIN1499146
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (10)
Cat. No. ABIN1499147
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN680518
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN517523
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN517519
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN517518
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7138862
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN517517
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN3182060
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7239173
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN548441
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN961214
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN626072
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7158354
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LIM Domain Kinase 1 抗体

Yang, He, Zhang, Chen, Kong, Xie, Jia, Liu, Zhou: "Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain." in: Neuropharmacology, Vol. 125, pp. 284-294, (2018) (PubMed).

Gupta, Yadav, Pavuluri, Morley, Stairs, Dravid: "Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity." in: Neuropharmacology, Vol. 93, pp. 274-84, (2015) (PubMed).

Zhou, Liu, Luo, Zhou, Xia, Chen, Zhou, Zou, Cao, Cao: "MiR-20a inhibits cutaneous squamous cell carcinoma metastasis and proliferation by directly targeting LIMK1." in: Cancer biology & therapy, Vol. 15, Issue 10, pp. 1340-9, (2015) (PubMed).

Park, Agnihotri, Golbourn, Bertrand, Luck, Sabha, Smith, Byron, Zadeh, Croul, Berens, Rutka: "Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway." in: Oncotarget, Vol. 5, Issue 19, pp. 9382-95, (2014) (PubMed).

Zhang, Gan, Zhou: "Immunohistochemical investigation of the correlation between LIM kinase 1 expression and development and progression of human ovarian carcinoma." in: The Journal of international medical research, Vol. 40, Issue 3, pp. 1067-73, (2013) (PubMed).

Li, Ponten, dos Remedios: "The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development." in: Proteomics, Vol. 12, Issue 2, pp. 203-25, (2012) (PubMed).

Guo, Lv, Tian, Hu, Wang, Sui, Jiang, Ruan, Nan: "Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma." in: Carcinogenesis, Vol. 32, Issue 12, pp. 1897-904, (2011) (PubMed).

Li, Ke, Li, Liu, Zhu, Li: "DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 1, pp. 70-9, (2009) (PubMed).

Kobayashi, Nishita, Mishima, Ohashi, Mizuno: "MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration." in: The EMBO journal, Vol. 25, Issue 4, pp. 713-26, (2006) (PubMed).

Soosairajah, Maiti, Wiggan, Sarmiere, Moussi, Sarcevic, Sampath, Bamburg, Bernard: "Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin." in: The EMBO journal, Vol. 24, Issue 3, pp. 473-86, (2005) (PubMed).

Aliases for LIM Domain Kinase 1 抗体

LIM domain kinase 1 (LIMK1) 抗体
LIM domain kinase 1a (limk1a) 抗体
LIM domain kinase 1 (limk1) 抗体
LIM domain kinase 1 (CpipJ_CPIJ000717) 抗体
LIM domain kinase 1 (LOC413152) 抗体
LIM domain kinase 1 (Limk1) 抗体
LIM domain kinase 1 L homeolog (limk1.L) 抗体
LIM-domain containing, protein kinase (Limk1) 抗体
GB16654 抗体
LIMK 抗体
LIMK-1 抗体
limk1 抗体
LIMK1 抗体
xlimk1 抗体
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