anti-小鼠 APP 抗体 for Western Blotting

Recommended APP Antibody (supplied by: Log in to see )

抗原
Amyloid beta (A4) Precursor Protein (APP) 抗体
  • AAA
  • ABETA
  • ABPP
  • AD1
  • APPI
  • CTFgamma
  • CVAP
  • PN-II
  • PN2
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • APP-like
  • APPL
  • Abeta
  • BcDNA:GH04413
  • CG7727
  • Dmel\\CG7727
  • EG:65F1.5
  • appl
  • Abpp
  • Adap
  • Ag
  • Cvap
  • E030013M08Rik
  • betaApp
  • app
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740
  • amyloid beta precursor protein
  • amyloid beta (A4) precursor protein
  • beta amyloid protein precursor-like
  • amyloid beta (A4) precursor protein a
  • amyloid beta precursor protein L homeolog
  • APP
  • app
  • Appl
  • App
  • appa
  • app.L
抗原表位
AA 672-713, C-Term
105
102
70
39
37
32
31
19
17
15
15
14
14
13
12
10
9
7
7
7
7
6
6
6
5
5
5
5
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
931
383
361
40
27
22
19
18
15
13
12
10
7
7
4
4
4
3
2
2
1
宿主

646
261
51
7
2
克隆类型
多克隆
标记
This APP antibody is un-conjugated
51
43
41
17
16
14
14
14
13
13
13
13
13
13
13
8
8
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
668
405
293
159
158
122
82
57
40
36
17
15
15
10
8
3
3
2
1
1
1
选项
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产品编号 ABIN3043787
$ 280.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2534187 ABIN2777738 WB Rabbit Middle Region Log in to see Polyclonal 1
3.2534187 ABIN2777739 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
3.2534187 ABIN2787850 WB Rabbit C-Term Log in to see Polyclonal 0
3.2534187 ABIN2779739 IHC WB Rabbit C-Term Log in to see Polyclonal 0
3.2534187 ABIN2855011 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
3.2534187 ABIN2465038 ELISA WB Goat N-Term Log in to see Polyclonal 0
3.2534187 ABIN358841 EIA WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 5
3.2534187 ABIN1449275 WB Mouse IgG1 AA 18-38 Log in to see 3-00E-009 3
3.2534187 ABIN2464967 ELISA WB Goat N-Term Log in to see Polyclonal 0
3.2534187 ABIN4281249 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 1
3.2534187 ABIN1871049 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2534187 ABIN1532190 IF IHC ELISA WB Rabbit IgG AA 711-760 Log in to see Polyclonal 0
3.2534187 ABIN1531173 IF IHC ELISA WB Rabbit IgG AA 711-760, pThr743 Log in to see Polyclonal 0
3.2534187 ABIN317496 EIA IHC (p) WB Mouse IgG2b AA 18-289 Log in to see J4H9 0
3.2534187 ABIN2451920 IC IF IHC WB Rabbit C-Term, AA 671-695 Log in to see Polyclonal 5
3.2534187 ABIN1869978 IHC WB Rabbit IgG pThr743 Log in to see Polyclonal 0
3.2534187 ABIN2451919 IC IF WB Rabbit N-Term, AA 18-38 Log in to see Polyclonal 4
3.2534187 ABIN1869980 WB Rabbit IgG pThr668 Log in to see Polyclonal 0
3.2534187 ABIN1871051 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2534187 ABIN1858064 ICC IHC WB Rabbit IgG AA 672-770 Log in to see Polyclonal 0

General

抗原 Amyloid beta (A4) Precursor Protein (APP) 抗体
抗原表位 AA 672-713, C-Term
(105), (102), (70), (39), (37), (32), (31), (19), (17), (15), (15), (14), (14), (13), (12), (10), (9), (7), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(931), (383), (361), (40), (27), (22), (19), (18), (15), (13), (12), (10), (7), (7), (4), (4), (4), (3), (2), (2), (1)
宿主
(646), (261), (51), (7), (2)
克隆类型
多克隆
标记 This APP antibody is un-conjugated
(51), (43), (41), (17), (16), (14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(668), (405), (293), (159), (158), (122), (82), (57), (40), (36), (17), (15), (15), (10), (8), (3), (3), (2), (1), (1), (1)
Pubmed 4个引用可参考
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APP抗体详情

APP目标详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN3043787) 图像
原理 Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
序列 DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
交叉反应 (详细) No cross reactivity with other proteins.
产品特性 Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: amyloid beta (A4) precursor protein
Protein Name: Amyloid beta A4 protein
纯化方法 Immunogen affinity purified.
免疫原 A synthetic peptide corresponding to a sequence at the C-terminus of human APP(672-713aa DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA), different from the related mouse and rat sequences by three amino acids.
亚型 IgG

APP目标详情

APP抗体详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN3043787) 图像 回页首
抗原
别名 APP (APP Antibody 摘要)
背景 Beta Amyloid, also called Abeta or Abeta, denotes peptides of 36-43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

Synonyms: A4 antibody|A4 antibody|A4_HUMAN antibody|AAA antibody|AAA antibody|ABETA antibody|ABETA antibody|ABPP antibody|ABPP antibody|AD1 antibody|AICD-50 antibody|AICD-57 antibody|AICD-59 antibody|AID(50) antibody|AID(57) antibody|AID(59) antibody|Alzheimer disease amyloid protein antibody|Alzheimers Disease Amyloid Protein antibody|Amyloid B antibody|amyloid beta (A4) precursor protein antibody|amyloid beta A4 protein antibody|Amyloid Beta A4 Protein Precursor antibody|Amyloid Beta antibody|Amyloid intracellular domain 50 antibody|Amyloid intracellular domain 57 antibody|Amyloid intracellular domain 59 antibody|Amyloid of Aging and Alzheimer Disease antibody|APP antibody|APPI antibody|APPI antibody|B Amyloid antibody|Beta APP antibody|beta-amyloid peptide antibody|Beta-APP40 antibody|Beta-APP42 antibody|C31 antibody|Cerebral Vascular Amyloid Peptide antibody|CTFgamma antibody|CVAP antibody|CVAP antibody|Gamma-CTF(50)antibody|Gamma-CTF(57) antibody|Gamma-CTF(59) antibody|peptidase nexin-II antibody|PN II antibody|PN-II antibody|PN2 antibody|PreA4 antibody|PreA4 antibody|Protease nexin II antibody|Protease nexin-II antibody|S-APP-alpha antibody|S-APP-beta antibody
基因ID 351
UniProt P05067
途径 Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

使用细节

APP抗体详情 APP目标详情 贮存及处理 References for anti-APP antibody (ABIN3043787) 图像 回页首
应用备注 WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for APP is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制 仅限研究用

贮存及处理

APP抗体详情 APP目标详情 使用细节 References for anti-APP antibody (ABIN3043787) 图像 回页首
状态 Lyophilized
溶解方式 Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
浓度 500 μg/mL
缓冲液 Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-APP antibody (ABIN3043787)

APP抗体详情 APP目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Sun, Zhou, Yi, Jiang, Yuan: "Lead-induced morphological changes and amyloid precursor protein accumulation in adult rat hippocampus." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 513-7, 2014

Qin, Yao, Huang: "Effects of compound danshen tablets on spatial cognition and expression of brain beta-amyloid precursor protein in a rat model of Alzheimer's disease." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine, Vol. 32, Issue 1, pp. 63-6, 2012

Li, Li, Huang, Kan, Wang, Wu, Yin, Yao: "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." in: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, 2011

Nie, Luo, Huang, Gong, Wu, Shi: "Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus." in: European journal of pharmacology, Vol. 626, Issue 2-3, pp. 213-8, 2009

图像

APP抗体详情 APP目标详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN3043787) 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Mouse Brain Tissue
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Rat Brain Tissue
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml WB: R...
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml Lane ...