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CRTC2 抗体

(CREB Regulated Transcription Coactivator 2 (CRTC2))
This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010].
CRTC2 抗体  (C-Term) CRTC2 抗体  (C-Term) CRTC2 抗体 (C-Term) (ABIN5539499)

Verified CRTC2 适用: 人, 大鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

CRTC2 抗体 CRTC2 抗体 CRTC2 抗体 (ABIN969067)

CRTC2 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B10 unconjugated

CRTC2 抗体  (pSer171) CRTC2 抗体  (pSer171) CRTC2 抗体 (pSer171) (ABIN745988)

CRTC2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

CRTC2 抗体 by Grade

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CRTC2 抗体 by 适用

Find CRTC2 抗体 for a variety of species such as anti-Human CRTC2, anti-Mouse CRTC2, anti-Rat CRTC2. The species listed below are among those available. Click on a link to go to the corresponding products.

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CRTC2 抗体 by 抗体来源

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CRTC2 抗体 by 抗原表位

Find CRTC2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CRTC2 抗体 by 克隆形成能力

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CRTC2 抗体 by 克隆

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CRTC2 抗体 by 标记

Find CRTC2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CRTC2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF, FACS
Validations
  • (6)
Cat. No. ABIN5539499
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (3)
  • (4)
Cat. No. ABIN969067
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS
Validations
  • (4)
  • (2)
Cat. No. ABIN745988
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN531261
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7148679
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN625819
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN566934
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN1590074
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN701260
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN745990
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
Cat. No. ABIN874508
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
Cat. No. ABIN874512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
Cat. No. ABIN874509
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
Cat. No. ABIN874510
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
Cat. No. ABIN2807131
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CRTC2 抗体

Slocum, Skoko, Wakabayashi, Aja, Yamamoto, Kensler, Chartoumpekis: "Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet." in: Archives of biochemistry and biophysics, Vol. 591, pp. 57-65, (2016) (PubMed).

Seok, Fu, Choi, Li, Zhu, Kumar, Sun, Yoon, Kang, Zhong, Ma, Kemper, Kemper: "Transcriptional regulation of autophagy by an FXR-CREB axis." in: Nature, Vol. 516, Issue 7529, pp. 108-11, (2015) (PubMed).

Tian, Zhao, Sun, Zhi, Cheng, Zhou, Hu: "CRTC2 enhances HBV transcription and replication by inducing PGC1? expression." in: Virology journal, Vol. 11, Issue 1, pp. 30, (2014) (PubMed).

Cicerchi, Li, Kratzer, Garcia, Roncal-Jimenez, Tanabe, Hunter, Rivard, Sautin, Gaucher, Johnson, Lanaspa: "Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 8, pp. 3339-50, (2014) (PubMed).

Jeanneteau, Lambert, Ismaili, Bath, Lee, Garabedian, Chao: "BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 4, pp. 1305-10, (2012) (PubMed).

Liu, Coello, Grinevich, Aguilera: "Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription." in: Endocrinology, Vol. 151, Issue 3, pp. 1109-18, (2010) (PubMed).

Murata, Sato, Nakayama, Kudoh, Iwahori, Isomura, Tajima, Hishiki, Ohshima, Hijikata, Shimotohno, Tsurumi: "TORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 8033-41, (2009) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Dentin, Liu, Koo, Hedrick, Vargas, Heredia, Yates, Montminy: "Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2." in: Nature, Vol. 449, Issue 7160, pp. 366-9, (2007) (PubMed).

Aliases for CRTC2 抗体

CREB regulated transcription coactivator 2 (CRTC2) 抗体
CREB regulated transcription coactivator 2 (Crtc2) 抗体
4632407F12Rik 抗体
CRTC2 抗体
mTORC2 抗体
RGD1308903 抗体
TORC-2 抗体
TORC2 抗体
Torc2 抗体
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