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CIITA 抗体

(Class II, Major Histocompatibility Complex, Transactivator (CIITA))
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the 'master control factor' for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. [provided by RefSeq, Jul 2008].
CIITA 抗体  (AA 945-1130) CIITA 抗体  (AA 945-1130) CIITA 抗体 (AA 945-1130) (ABIN4886541)

CIITA 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

CIITA 抗体  (Internal Region) CIITA 抗体  (Internal Region) CIITA 抗体 (Internal Region) (ABIN6257104)

CIITA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

CIITA 抗体  (AA 1) CIITA 抗体  (AA 1) CIITA 抗体 (AA 1) (ABIN97339)

CIITA 适用: Pig WB 宿主: 兔 Polyclonal unconjugated

CIITA 抗体 by 适用

Find CIITA 抗体 for a variety of species such as anti-Human CIITA, anti-Mouse CIITA, anti-Rat CIITA. The species listed below are among those available. Click on a link to go to the corresponding products.

CIITA 抗体 by 应用范围

Find CIITA 抗体 validated for a specific application such as WB, ELISA, IF, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

CIITA 抗体 by 抗体来源

Find CIITA 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CIITA 抗体 by 抗原表位

Find CIITA 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CIITA 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CIITA 抗体. Click on a link to go to the corresponding products.

CIITA 抗体 by 标记

Find CIITA 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CIITA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN4886541
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257104
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN97339
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6736073
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6742736
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7266403
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN6284770
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF
Validations
Cat. No. ABIN6991412
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7464900
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
Cat. No. ABIN352252
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN345973
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN1533701
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2780332
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2779823
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, EIA
Validations
  • (1)
Cat. No. ABIN783727
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our CIITA 抗体

Majumder, Lee, Rahmberg, Kumar, Mi, Scharer, Boss: "A super enhancer controls expression and chromatin architecture within the MHC class II locus." in: The Journal of experimental medicine, Vol. 217, Issue 2, (2020) (PubMed).

Sun, Huang, Yu, Zhang, Xu, Zhang, Li, Dong, Guo, Wang: "Autoregulatory loop between TGF-β1/miR-411-5p/SPRY4 and MAPK pathway in rhabdomyosarcoma modulates proliferation and differentiation." in: Cell death & disease, Vol. 6, pp. e1859, (2016) (PubMed).

Scharer, Choi, Barwick, Majumder, Lohsen, Boss: "Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment." in: Nucleic acids research, Vol. 43, Issue 6, pp. 3128-42, (2015) (PubMed).

Koues, Dudley, Mehta, Greer: "The 19S proteasome positively regulates histone methylation at cytokine inducible genes." in: Biochimica et biophysica acta, Vol. 1789, Issue 11-12, pp. 691-701, (2009) (PubMed).

Aliases for CIITA 抗体

class II, major histocompatibility complex, transactivator (CIITA) 抗体
class II major histocompatibility complex transactivator (CIITA) 抗体
MHC class II transactivator (LOC710761) 抗体
class II, major histocompatibility complex, transactivator (ciita) 抗体
MHC class II transactivator (LOC100443575) 抗体
class II transactivator (Ciita) 抗体
MHC class II transactivator (LOC100736732) 抗体
class II, major histocompatibility complex, transactivator (Ciita) 抗体
C2ta 抗体
C2TA 抗体
CIITA 抗体
CIITAIV 抗体
EG669998 抗体
Gm9475 抗体
MHC2TA 抗体
Mhc2ta 抗体
NLRA 抗体
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