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PDE8A 抗体

(phosphodiesterase 8A (PDE8A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011].
PDE8A 抗体  (AA 32-121) PDE8A 抗体  (AA 32-121) PDE8A 抗体 (AA 32-121) (ABIN518727)

PDE8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated

PDE8A 抗体  (Leu572) PDE8A 抗体  (Leu572) PDE8A 抗体 (Leu572) (ABIN542843)

PDE8A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

PDE8A 抗体  (AA 596-829) PDE8A 抗体  (AA 596-829) PDE8A 抗体 (AA 596-829) (ABIN7155164)

PDE8A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PDE8A 抗体 by 适用

Find PDE8A 抗体 for a variety of species such as anti-Human PDE8A, anti-Mouse PDE8A, anti-Rat PDE8A. The species listed below are among those available. Click on a link to go to the corresponding products.

PDE8A 抗体 by 应用范围

Find PDE8A 抗体 validated for a specific application such as ELISA, IHC, WB, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDE8A 抗体 by 抗体来源

Find PDE8A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PDE8A 抗体 by 抗原表位

Find PDE8A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDE8A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PDE8A 抗体. Click on a link to go to the corresponding products.

PDE8A 抗体 by 克隆

Find PDE8A 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PDE8A 抗体 by 标记

Find PDE8A 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDE8A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN518727
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN542843
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7155164
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746532
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit, Rat
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746531
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1690735
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN518726
Quantity 50 μL
Datasheet Datasheet
Reactivity Dog, Gorilla, Horse, Human, Mouse, Pig, Rabbit
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN5585400
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6145368
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ICC
Validations
  • (1)
Cat. No. ABIN2855642
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2787371
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (2)
Cat. No. ABIN2787372
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5537478
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN356970
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155167
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDE8A 抗体

Maréchal, Guillemette, Goupil, Blondin, Leclerc, Richard: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Kelly, Adamowicz, Bove, Hartman, Mariga, Pathak, Reinhart, Romegialli, Kleiman: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).

Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

Kruse, Møller, Kruuse: "Distribution of PDE8A in the nervous system of the Sprague-Dawley rat." in: Journal of chemical neuroanatomy, Vol. 42, Issue 3, pp. 184-91, (2012) (PubMed).

Bol, Booiman, Bunnik, Moerland, van Dort, Strauss, Sieberer, Schuitemaker, Kootstra, van t Wout: "Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages." in: Virology, Vol. 420, Issue 1, pp. 32-42, (2011) (PubMed).

Wu, Wang: "Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 51, pp. 17634-9, (2004) (PubMed).

Gamanuma, Yuasa, Sasaki, Sakurai, Kotera, Omori: "Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans." in: Cellular signalling, Vol. 15, Issue 6, pp. 565-74, (2003) (PubMed).

Shahan, Sorenson, Simpson, Kefalides, Lewis: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, (2000) (PubMed).

Yang, Malek, Desiderio: "An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20832-40, (1995) (PubMed).

Aliases for PDE8A 抗体

phosphodiesterase 8A (PDE8A) 抗体
phosphodiesterase 8A (Pde8a) 抗体
phosphodiesterase 8A (pde8a) 抗体
AI551852 抗体
HsT19550 抗体
Pde8 抗体
PDE8A 抗体
Pde8a 抗体
RNPDE8A 抗体
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