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Chicken Monoclonal GNB2L1 Primary Antibody for BI, IP - ABIN967796
Birikh, Sklan, Shoham, Soreq: Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. in Proceedings of the National Academy of Sciences of the United States of America 2003
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Chicken Monoclonal GNB2L1 Primary Antibody for BI, IP - ABIN967797
Smart, Ying, Anderson: Hormonal regulation of caveolae internalization. in The Journal of cell biology 1996
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Human Polyclonal GNB2L1 Primary Antibody for IHC, IHC (p) - ABIN4892013
Yang, Pu, Qin, You, Ke: Characterization of receptor of activated C kinase 1 (RACK1) and functional analysis during larval metamorphosis of the oyster Crassostrea angulata. in Gene 2014
RACK1 emerges as an important marker of malignancy which may contribute to progress in the diagnosis of melanomas in both human and veterinary medicine.[RACK1]
Leads to the enhanced and previously un-described interaction of RACK1 and TCTP (显示 TPT1 抗体).
urther investigation indicated that p205 may disturb the formation of Runx2 (显示 RUNX2 抗体)/Ids (显示 IDS 抗体) complex and free more Runx2 (显示 RUNX2 抗体) to induce the differentiation process. Taken together, our findings demonstrated for the first time that p205 functions as an activator in osteoblast differentiation.
RACK1 competes with Rab40C (显示 RAB40C 抗体) for binding to the ANKR2 domain of Varp (显示 ANKRD27 抗体) and regulates dendrite outgrowth through stabilization of Varp (显示 ANKRD27 抗体) in mouse melanocytes
Data show that receptor for activated C-kinase 1 (RACK1) and vascular endothelial growth factor (VEGF) expression is up-regulated after choroidal neovascularization (CNV) formation.
RACK1 is a novel factor required for adipocyte differentiation.
deficit of RACK1 in hippocampus impairs the ability of learning and memory in mice via up regulating autophagy
RACK1 plays an important role in the maintenance of morphine conditioned place preference, likely via activation of ERK (显示 EPHB2 抗体)-CREB (显示 CREB1 抗体) pathway in hippocampus.
Thr50 phosphorylation of RACK1 enhances its direct binding to Vps15, Atg14L, and Beclin 1 (显示 BECN1 抗体), thereby promoting the assembly of the autophagy-initiation complex.
These findings suggest that RACK1 specifies the RANKL (显示 TNFSF11 抗体)-stimulated activation of p38 MAPK (显示 MAPK14 抗体) by facilitating the association of MKK6 (显示 MAP2K6 抗体) with TAK1 (显示 NR2C2 抗体)
RACK1 stimulates the translation of collagen 1alpha 1, snail (显示 SNAI1 抗体) and cyclin E1 (显示 CCNE1 抗体) in hepatic stellate cells.
the depletion of ribosomal RACK1 alters the capacity of the ribosome to translate specific mRNAs, resulting in selective translation of mRNAs of genes for non-canonical autophagy induction.
This work has significantly advanced our understanding of the RACK1/PP2A (显示 PPP2R4 抗体) complex and suggests a pro-carcinogenic role for the RACK1/PP2A (显示 PPP2R4 抗体) interaction. This work suggests that approaches to target the RACK1/PP2A (显示 PPP2R4 抗体) complex are a viable option to regulate PP2A (显示 PPP2R4 抗体) activity and identifies a novel potential therapeutic target in the treatment of breast cancer.
Our analysis shows that most of the interaction partners with putative regulatory functions have binding sites that are available on ribosomal RACK1, supporting the role of RACK1 as a ribosomal signaling hub.
This supports PDE4D5 and RACK1 as potential regulators of cell adhesion, spreading and migration through the non-classical exchange protein activated by cyclic AMP (EPAC1)/Rap1 signalling route
In this review we summarize this evidence and examine the mechanisms that underlie the contribution of RACK1 to the various stages of cell migration and invasion.
Analysis of deletion constructs of SERBP1 (显示 SERBP1 抗体) showed that the C-terminal third of the SERBP1 (显示 SERBP1 抗体) protein, which contains one of its two substrate sites for protein arginine N-methyltransferase 1 (PRMT1 (显示 PRMT1 抗体)), is necessary and sufficient for it to interact with RACK1
identification of regulatory elements in the promoter of RACK1 shed some light on its transcriptional modulation in physiological and pathological context.These and other informations suggest that a better understanding of RACK1 transcriptional regulation is essential to unravel its role.
Data indicate that OR3A4 upregulation contributes to metastasis and tumorigenesis in gastric cancer by regulating the activation of PDLIM2 (显示 PDLIM2 抗体), MACC1 (显示 MACC1 抗体), NTN4, and GNB2L1.
High RACK1 expression is associated with imatinib resistance in gastrointestinal stromal tumor.
The upregulation of RACK1 can promote the proliferation and invasion of nasopharyngeal carcinoma by regulating the PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体)/FAK (显示 PTK2 抗体) signal pathway.
Rack1 has a dominant-negative effect on Vangl2 (显示 VANGL2 抗体) localization and gastrulation.
These results suggest that PKCepsilon (显示 PRKCE 抗体) signaling in the basal airway cell may involve RACK1; however, PKCepsilon (显示 PRKCE 抗体) regulation in ciliated cells uses RACK1-independent pathways.
Lactobacillus casei pretreatment triggers the TLR mediated and rack-1 dependent p38 MAPK (显示 MAPK14 抗体) signaling pathway in nematodes. rack-1 is necessary in activating the p38 MAPK (显示 MAPK14 抗体) pathway by Lactobacillus casei.
RACK-1 controls the biogenesis of a subset of miRNAs, including let-7, and in this way plays a role in the heterochronic gene pathway during C. elegans development.
RACK1 can contribute to the recruitment of miRISC to the site of translation, and support a post-initiation mode of miRNA-mediated gene repression.
show that depletion of Caenorhabditis elegans RACK-1, which leads to short astral microtubules during prometaphase, specifically affects maintenance of cortical PAR (显示 AFG3L2 抗体) domains and Dynamin localization
These studies pinpoint RACK-1 as a component of a novel signaling pathway involving Rac (显示 AKT1 抗体) GTPases and UNC-115/abLIM (显示 ABLIM1 抗体).
suggest a mechanism by which RACK-1 directs the dynactin (显示 DCTN1 抗体)-dependent redistribution of recycling endosomes during the cell cycle
may act as a receptor for activated protein kinase C
guanine nucleotide binding protein, beta 2, related sequence 1
, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
, G-beta-like protein
, guanine nucleotide-binding protein beta subunit
, activated protein kinase C receptor
, guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 sequence 1
, guanine nucleotide binding protein related
, guanine nucleotide binding protein, beta-2, related sequence 1
, guanine nucleotide-binding protein subunit beta-2-like 1
, receptor for activated C kinase
, receptor of activated protein kinase C 1
, guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1
, guanine nucleotide binding protein, beta polypeptide 2-like 1
, protein kinase C receptor
, receptor for activated protein kinase C
, cell proliferation-inducing gene 21 protein
, guanine nucleotide-binding protein subunit beta-like protein 12.3
, human lung cancer oncogene 7 protein
, lung cancer oncogene 7
, proliferation-inducing gene 21
, protein homologous to chicken B complex protein, guanine nucleotide binding
, receptor for activated C kinase 1
, receptor of activated protein kinase C
, Guanine nucleotide-binding protein beta subunit2-like 1
, MHC B complex protein 12.3
, guanine nucleotide binding 12.3
, guanine nucleotide-binding protein beta subunit 2-like 1
, G-beta like protein