anti-豚鼠 Adenylate Cyclase 10 (Soluble) 抗体 for Western Blotting

Recommended Adenylate Cyclase 10 (Soluble) Antibody

抗原
Adenylate Cyclase 10 (Soluble) (ADCY10) 抗体
  • HCA2
  • RP1-313L4.2
  • SAC
  • SACI
  • Sacy
  • Sac
  • 4930431D04Rik
  • 4931412F17
  • sAC
  • ADCY10
  • SACY
  • adenylate cyclase 10
  • adenylate cyclase 10 (soluble)
  • ADCY10
  • Adcy10
抗原表位
N-Term
15
9
7
7
7
4
2
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
44
23
22
3
2
1
1
宿主

47
1
克隆类型
多克隆
标记
非结合性
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
31
22
15
13
6
6
6
3
1
1
选项

Available images

产品编号 ABIN2782970
$ 319.00
加上运输费 $45.00

General

抗原 Adenylate Cyclase 10 (Soluble) (ADCY10) 抗体
抗原表位 N-Term
(15), (9), (7), (7), (7), (4), (2), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
(44), (23), (22), (3), (2), (1), (1)
宿主
(47), (1)
克隆类型
多克隆
标记 非结合性
(4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(31), (22), (15), (13), (6), (6), (6), (3), (1), (1)
Pubmed 2个引用可参考
Supplier

产品细节

目标详细情况 使用细节 贮存及处理 引用 图像
Blocking Peptide Blocking peptide for this product available: ABIN983376
序列 VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL
预测反应 Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human SAC

目标详细情况

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抗原
别名 SAC (ADCY10 Antibody 摘要)
背景 SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
Protein Interaction Partner: PTGIR, SSTR5,
Protein Size: 1610
分子量 187 kDa
基因ID 55811
NCBI登录号 NM_018417, NP_060887
UniProt Q96PN6
途径 cAMP Metabolic Process

使用细节

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应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 1610 AA

限制 仅限研究用

贮存及处理

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状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

引用

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有引用在:

Corredor, Trakhtenberg, Pita-Thomas, Jin, Hu, Goldberg: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, 2012

背景

Schmid, Sutto, Nlend, Horvath, Schmid, Buck, Levin, Conner, Fregien, Salathe: "Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP." in: The Journal of general physiology, Vol. 130, Issue 1, pp. 99-109, 2007

图像

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厂商提供的图像
Western Blotting (WB) image for anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (N-Term) antibody (ABIN2782970) WB Suggested Anti-SAC Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positi...