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Human alpha Fetoprotein Protein expressed in Human - ABIN934756
Lee, Nguyen, Sim: A nanoplasmonic biosensor for label-free multiplex detection of cancer biomarkers. in Biosensors & bioelectronics 2015
Show all 2 Pubmed References
Human alpha Fetoprotein Protein expressed in Human - ABIN934453
Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012
Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558
Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014
Human alpha Fetoprotein Protein expressed in Human - ABIN377076
Jee, Ang, Cha, Ang, Ling, Lim, Lee: Combinatorial bead-based peptide libraries improved for rapid and robust screenings. in Combinatorial chemistry & high throughput screening 2014
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (显示 CTNNB1 蛋白), suggesting that beta-catenin (显示 CTNNB1 蛋白) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (显示 VEGFC 蛋白) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (显示 GYS1 蛋白) accumula-tion and intracytoplasmic localization of beta-catenin (显示 CTNNB1 蛋白) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (显示 FOXA1 蛋白) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (显示 HRAS 蛋白) p21 genes
A murine Nkx2.8 (显示 NKX2-6 蛋白) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (显示 NR5A2 蛋白).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (显示 FOXA1 蛋白)
Identification of the distinct impact of circulating tumor derived AFP on NK-cell function and viability may be crucial to developing a strategy to ameliorate hepatocellular carcinoma patient NK-cell functional deficits.
The detection of ALT, AFP, AFP-L3, and GP73 (显示 GOLM1 蛋白) has a certain guiding significance to predict the risk of hepatocellular carcinoma in hepatic cirrhosis patients
Antibody therapy targeted at AFP-producing tumor cells showed an inhibitory effect on the PI3K/AKT pathway via the liberation, restoration and functional stabilization of PTEN. PTEN simultaneously induced both P53 activation and intracellular translocation of GLUT1, since these are closely associated with PTEN.
Incorporation AFP status into the BCLC staging system to modify the recommended treatment of patients with stage C hepatocellular carcinoma.
we used alpha-fetoprotein (AFP), a specific liver cancer marker, as an example to determine whether peptide-MHC (显示 HLAE 蛋白) complexes can be targets for CAR T-cell therapy against solid tumors.in an established intraperitoneal liver cancer xenograft model, AFP-CAR T cells showed robust antitumor activity
miR (显示 MLXIP 蛋白)-620, miR (显示 MLXIP 蛋白)-1236 and miR (显示 MLXIP 蛋白)-1270 are critical factors in the post-transcriptional regulation of AFP in hepatitis B infected hepatoma cells. Icaritin can counteract the effect of HBV.
BWS (显示 CDKN1C 蛋白) registries and prospective clinical studies will assess the most appropriate means to screen for hepatoblastoma, whether aFP-screened patients have additional survival benefit over patients screened by US only, and whether the outcome is improved by earlier detection
p55PIK significantly stimulated the expression of AFP by activating NF-kappaB (显示 NFKB1 蛋白) signaling pathway in hepatocellular carcinoma cells.
Irregular MIP (显示 TNPO1 蛋白) pattern by CEUS and high level of serum AFP-L3 were independent risk factors for poor outcome after successful RFA (显示 RPA1 蛋白). The Patients with these findings should be considered as special high-risk group in early-stage HCC (显示 FAM126A 蛋白).
our data suggest that HBeAg seroconversion and liver cirrhosis are associated with the occurrence of HCC (显示 FAM126A 蛋白) and that a surveillance system with regular measurement of AFP to watch for the occurrence of HCC (显示 FAM126A 蛋白) may be mandatory for children and young patients with chronic HBV infection.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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