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CASC5 蛋白

(Cancer Susceptibility Candidate 5 (CASC5))

The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11\;15)(q23\;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013].

recommended

CASC5 Protein (AA 3-98) (GST tag) (ABIN1348085)

CASC5 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

CASC5 Protein (AA 1-1612) (His tag) (ABIN3135614)

Crystallography grade CASC5 宿主: 小鼠宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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recommended

CASC5 Protein (AA 1-230) (His tag) (ABIN7420573)

CASC5 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant >95 % WB, SDS, Imm, PC

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CASC5 蛋白 by Grade

Find CASC5 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CASC5 蛋白 by Origin

Find CASC5 蛋白 for a variety of species such as anti-Mouse CASC5, anti-Human CASC5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASC5 蛋白 by Source

Here you will find CASC5 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CASC5 蛋白 by 蛋白类型

Here you can find CASC5 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CASC5 蛋白 by 应用范围

Find CASC5 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CASC5 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CASC5 Protein (AA 3-98) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348085

Quantity 10 μg

Datasheet Datasheet

CASC5 Protein (AA 1-1612) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3135614

Quantity 1 mg

Datasheet Datasheet

CASC5 Protein (AA 1-230) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7420573

Quantity 100 μg

Datasheet Datasheet

CASC5 Protein (AA 1-277) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7423420

Quantity 100 μg

Datasheet Datasheet

CASC5 蛋白

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6119589

Quantity 100 μg

Datasheet Datasheet

Aliases for CASC5 蛋白

kinetochore scaffold 1 (KNL1) 蛋白
kinetochore scaffold 1 (Knl1) 蛋白
Kinetochore null protein 1 (knl-1) 蛋白
2310043D08Rik 蛋白
5730505K17Rik 蛋白
AF15Q14 蛋白
CT29 蛋白
D40 蛋白
hKNL-1 蛋白
hSpc105 蛋白
KNL1 蛋白
PPP1R55 蛋白
Rad51 蛋白
Spc7 蛋白

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CASC5 蛋白 by Grade

CASC5 蛋白 by Origin

CASC5 蛋白 by Source

CASC5 蛋白 by 蛋白类型

CASC5 蛋白 by 应用范围

Popular CASC5 蛋白

Aliases for CASC5 蛋白

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