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Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 产品

(Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity\; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008].

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Featured Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Categories

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 抗体

High quality antibodies with extensive validation data.

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN674529
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6139316
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7010005
Quantity 60 μL
Datasheet Datasheet

Recommended Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955240
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955241
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966233
Quantity 96 tests
Datasheet Datasheet

Recommended Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350929
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350931
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350933
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Products

AboulWafa, Daabees, Badawi: "2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study." in: Bioorganic chemistry, Vol. 99, pp. 103798, (2020) (PubMed).

Assisi, Pelagalli, Squillacioti, Liguori, Annunziata, Mirabella: "Orexin A-Mediated Modulation of Reproductive Activities in Testis of Normal and Cryptorchid Dogs: Possible Model for Studying Relationships Between Energy Metabolism and Reproductive Control." in: Frontiers in endocrinology, Vol. 10, pp. 816, (2019) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Giles, Jindal, Wellberg, Schedin, Anderson, Thor, Edwards, MacLean, Schedin: "Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 50, (2018) (PubMed).

Ding, Li, Wang, Wang, Wu, Chen, Lv, Wang, Huang: "Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristics." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 173, (2018) (PubMed).

Rodríguez-Castelán, Méndez-Tepepa, Carrillo-Portillo, Anaya-Hernández, Rodríguez-Antolín, Zambrano, Castelán, Cuevas-Romero: "Hypothyroidism Reduces the Size of Ovarian Follicles and Promotes Hypertrophy of Periovarian Fat with Infiltration of Macrophages in Adult Rabbits." in: BioMed research international, Vol. 2017, pp. 3795950, (2017) (PubMed).

Gan, Chen, Deng, Yuan, Kang, Qiu, Sun, Han, Hu, Li, Wang: "Establishment of an in vitro culture model of theca cells from hierarchical follicles in ducks." in: Bioscience reports, Vol. 37, Issue 3, (2017) (PubMed).

Zhang, Zhang, Zhang, Lu, Li, Cui: "MiRNA-143 mediates the proliferative signaling pathway of FSH and regulates estradiol production." in: The Journal of endocrinology, Vol. 234, Issue 1, pp. 1-14, (2017) (PubMed).

Dean, Nilsen, Loughlin, Salt, MacLean: "Metformin Reverses Development of Pulmonary Hypertension via Aromatase Inhibition." in: Hypertension (Dallas, Tex. : 1979), Vol. 68, Issue 2, pp. 446-54, (2017) (PubMed).

Licznerska, Szaefer, Wierzchowski, Sobierajska, Baer-Dubowska: "Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation." in: Molecular and cellular biochemistry, Vol. 425, Issue 1-2, pp. 169-179, (2017) (PubMed).

Synonyms and alternative names related to Cytochrome P450, Family 19, Subfamily A, Polypeptide 1

cytochrome P450 family 19 subfamily A member 1 (CYP19A1), cytochrome P450, family 19, subfamily a, polypeptide 1 (Cyp19a1), cytochrome P450 family 19 subfamily A member 1 L homeolog (cyp19a1.L), aromatase (SAV_2383), cytochrome P450 aromatase (pfcyp19b-tstr), cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), cytochrome P450 19A1 (CYP19A1), cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP19A1), cytochrome P450, family 19 (CYP19), cytochrome P450, family 19, subfamily A, polypeptide 1a (cyp19a1a), cytochrome P450, family 19, subfamily A, polypeptide 1b (cyp19a1b), cytochrome P450 19A1-like (LOC101174651), Ar, ar1, ArKO, ARO, aro, ARO1, AroB, Aromatase, CPV1, CYAR, CYP19, Cyp19, cyp19, Cyp19a, cyp19a, CYP19A1, CYP19a1, cyp19a1, CYP19a2, cyp19b, CYP19P1, CYPXIX, cypXIX, etID309862.18, Int-5, Int5, P-450AROM, P450 arom, p450arom, P450AROM, p450arom-A, P450aromA, P450aromB, zgc:92614, zgc:136541

Protein level used designations for Cytochrome P450, Family 19, Subfamily A, Polypeptide 1

  • aromatase
  • cytochrome P-450AROM
  • cytochrome P450 19A1
  • cytochrome P450, subfamily XIX (aromatization of androgens)
  • estrogen synthase
  • estrogen synthetase
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • CYPXIX
  • Cytochrome P450, 19, aromatase
  • P-450AROM
  • cytochrome P450 family 19 subfamily a
  • cytochrome P450, subfamily 19
  • p450 aromatase A
  • cytochrome P450 aromatase
  • cytochrome P450 17-alpha
  • CYPXIXA1
  • cytochrome P450 19 type I
  • cytochrome P450, family19, subfamily A, polypeptide 1
  • cytochrome P450, 19, aromatase
  • cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase
  • Cytochrome P-450AROM
  • Cytochrome P450 19A1
  • Estrogen synthase
  • aromatase cytochrome P450
  • cytochrome P450 19A1a
  • cytochrome P450, 19a
  • aromatase B
  • brain aromatase
  • cytochrome P450, 19b
  • cytochrome P450, family 19, subfamily A, polypeptide 1b
  • P-450 aromatase
  • cytochrome P-450 aromatase
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