We are preparing the requested document. Please wait, this may take a while...!
|抗原||Integrin alpha M (ITGAM) 抗体|
|适用||牛, 犬, 猫, 山羊, Mustelid, 猪 其他选择|
|标记||This CD11b antibody is un-conjugated 其他选择|
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
|Supplier||Log in to see|
CD11b抗体详情CD11b目标详情 使用细节 贮存及处理 References for anti-CD11b antibody (ABIN317369) 图像
|特异性||This antibody recognises the Canine CD11b cell surface antigen, a member of the alpha integrin family. Canine CD11b is expressed by granulocytes, monocytes and some macrophages.|
|产品特性||Synonyms: Integrin alpha-M, CR3A, MAC-1, MAC1, CR-3 alpha chain, Cell surface glycoprotein MAC-1subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11antigen-like family member B|
CD11b目标详情CD11b抗体详情 使用细节 贮存及处理 References for anti-CD11b antibody (ABIN317369) 图像 回页首
|别名||CD11b (ITGAM Antibody 摘要)|
|背景||CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8 % spleen cells, 44 % bone marrow cells and less than 1 % of thymocytes and is commonly used as a microglial marker in nervous tissue.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor|
|研究领域||Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells|
|途径||Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation|
使用细节CD11b抗体详情 CD11b目标详情 贮存及处理 References for anti-CD11b antibody (ABIN317369) 图像 回页首
Immunohistochemistry on Frozen Sections. Immunoprecipitation. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
贮存及处理CD11b抗体详情 CD11b目标详情 使用细节 References for anti-CD11b antibody (ABIN317369) 图像 回页首
|缓冲液||Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide as preservative.|
|注意事项||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|储存条件||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References for anti-CD11b antibody (ABIN317369)CD11b抗体详情 CD11b目标详情 使用细节 贮存及处理 图像 回页首
Brodersen, Bijlsma, Gori, Jensen, Chen, Dominguez, Haverson, Moore, Saalmüller, Sachs, Slierendrecht, Stokes, Vainio, Zuckermann, Aasted: "Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species." in: Veterinary immunology and immunopathology, Vol. 64, Issue 1, pp. 1-13, 1998